Evidence map›Paper›PMID 29202635›Full record

ReviewNucleus (Austin, Tex.)2017

The coupled effect of nucleosome organization on gene transcription level and transcriptional plasticity.

Jian Chen, En Li, Jinsheng Lai

Open access · goldAbstract readReview
In one paragraph

Review in Nucleus (Austin, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jian Chena State Key Laboratory of Agrobiotechnology and National Maize Improvement Center , Department of Plant Genetics and Breeding , China Agricultural University , Beijing , P. R. China.
En Lia State Key Laboratory of Agrobiotechnology and National Maize Improvement Center , Department of Plant Genetics and Breeding , China Agricultural University , Beijing , P. R. China.ORCID 0000-0001-7843-7702
Jinsheng Laia State Key Laboratory of Agrobiotechnology and National Maize Improvement Center , Department of Plant Genetics and Breeding , China Agricultural University , Beijing , P. R. China.
China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nucleosomes are the fundamental units of eukaryotic chromatin and can modulate the DNA accessibility for transcriptional regulatory elements. Many studies have demonstrated the effect of nucleosome organization on gene transcription level and transcriptional plasticity upon different conditions. Our recent study showed that nucleosome organization also plays an important role in modulating the plasticity of gene transcriptional status in maize. Here, we integrated our findings with previous studies on the role of nucleosome organization in regulation of gene transcription. We highlighted our recent finding that nucleosome organization plays an important role in determining the plasticity of gene transcription, beyond its role in regulating gene transcription level, particularly for intrinsically DNA-encoded nucleosome organization. We also discussed the features of sequence and structure of genes involved in affecting nucleosome organization around genes, as well as the potential mechanisms for overcoming the coupled effect of nucleosome organization on gene transcription level and transcriptional plasticity.

Indexed as

Transcription, GeneticAnimalsDNAHumansModels, BiologicalNucleosomesDNANucleosomesChromatingeneGene expressionnucleosometranscriptional plasticitytranscriptional regulationtranscription level

Identifiers

PMID29202635
PMCPMC5788551
OpenAlexW2773346184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.