Evidence map›Paper›PMID 29202325›Full record

ArticleBiomaterials2018

Co-delivery of human cancer-testis antigens with adjuvant in protein nanoparticles induces higher cell-mediated immune responses.

Medea Neek, Jo Anne Tucker, Tae Il Kim, Nicholas M Molino, Edward L Nelson, Szu-Wen Wang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Epigenetic Factors and ncRNAs in Testicular Cancer.International journal of molecular sciences · 2023
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Medea NeekDepartment of Chemical Engineering and Materials Science, University of California, Irvine, CA 92697, USA.
Jo Anne TuckerDepartment of Medicine, University of California, Irvine, CA 92697, USA.
Tae Il KimDepartment of Biomedical Engineering, University of California, Irvine, CA 92697, USA.
Nicholas M MolinoDepartment of Chemical Engineering and Materials Science, University of California, Irvine, CA 92697, USA.
Edward L NelsonDepartment of Medicine, University of California, Irvine, CA 92697, USA; Chao Family Comprehensive Cancer Center, University of California, Irvine, CA 92697, USA; Institute for Immunology, University of California, Irvine, CA 92697, USA.
Szu-Wen WangDepartment of Chemical Engineering and Materials Science, University of California, Irvine, CA 92697, USA; Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA; Chao Family Comprehensive Cancer Center, University of California, Irvine, CA 92697, USA. Electronic address: wangsw@uci.edu.
University of California, Irvine · US

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Christine Hui · 1994 to 2026
$57.9M
Nanoparticle-Modulated Response Against Tumor-Associated AntigensR21EB017995 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI WANG, SZU-WEN · 2014 to 2015
$380k
NCI NIH HHS P30 CA062203NIBIB NIH HHS R21 EB017995
6 · The paper itself

Abstract

Nanoparticles have attracted considerable interest as cancer vaccine delivery vehicles for inducing sufficient CD8

Indexed as

Immunity, CellularAdjuvants, ImmunologicAmino Acid SequenceAnimalsAntigens, NeoplasmCell Line, TumorCytotoxicity, ImmunologicDihydrolipoyllysine-Residue AcetyltransferaseEpitopesHumansImmunizationInterferon-gammaMice, TransgenicNanoparticlesOligodeoxyribonucleotidesPeptidesAdjuvants, ImmunologicAntigens, NeoplasmCPG-oligonucleotideDihydrolipoyllysine-Residue AcetyltransferaseEpitopesInterferon-gammaOligodeoxyribonucleotidesPeptidesCancer-testis antigen (CT)Cancer vaccineHLA-A2MAGE-A3NanoparticleNY-ESO-1

Identifiers

PMID29202325
PMCPMC5783197
OpenAlexW2769671991

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.