Evidence map›Paper›PMID 29202185›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2018

Clinical documentation variations and NLP system portability: a case study in asthma birth cohorts across institutions.

Sunghwan Sohn, Yanshan Wang, Chung-Il Wi, Elizabeth A Krusemark, Euijung Ryu, Mir H Ali, Young J Juhn, Hongfang Liu

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In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  17. Transfer Learning with Clinical Concept Embeddings from Large Language Models.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2025
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  20. Enhancing Cross-Domain Generalizability in Social Determinants of Health Extraction with Prompt-Tuning Large Language Models.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2025
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3 more citing papers are in PubMed but not listed here.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Sunghwan SohnDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.
Yanshan WangDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.
Chung-Il WiDepartment of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
Elizabeth A KrusemarkDepartment of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
Euijung RyuDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.
Mir H AliDepartment of Pediatrics, Sanford Children's Hospital, Sioux Falls, SD, USA.
Young J JuhnDepartment of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
Hongfang LiuDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.

Funding

Identification and characterization of children with asthma-associated comorbidities through computational and immune phenotypingR01HL126667 · NHLBI · MAYO CLINIC ROCHESTER · PI JUHN, YOUNG J, LIU, HONGFANG · 2015 to 2022
$4.3M
Secondary use of EMRs for surgical complication surveillanceR01EB019403 · NIBIB · MAYO CLINIC ROCHESTER · PI LIU, HONGFANG, STORLIE, CURTIS · 2015 to 2022
$3.8M
Enhanced Ascertainment of Asthma Status Via Natural Language ProcessingR21AI116839 · NIAID · MAYO CLINIC ROCHESTER · PI JUHN, YOUNG J, WU, STEPHEN TZE-INN · 2015 to 2016
$437k
NHLBI NIH HHS R01 HL126667NIAID NIH HHS R21 AI116839NIBIB NIH HHS R01 EB019403
6 · The paper itself

Abstract

objectiveTo assess clinical documentation variations across health care institutions using different electronic medical record systems and investigate how they affect natural language processing (NLP) system portability. MATERIALS AND

methodsBirth cohorts from Mayo Clinic and Sanford Children's Hospital (SCH) were used in this study (n = 298 for each). Documentation variations regarding asthma between the 2 cohorts were examined in various aspects: (1) overall corpus at the word level (ie, lexical variation), (2) topics and asthma-related concepts (ie, semantic variation), and (3) clinical note types (ie, process variation). We compared those statistics and explored NLP system portability for asthma ascertainment in 2 stages: prototype and refinement.

resultsThere exist notable lexical variations (word-level similarity = 0.669) and process variations (differences in major note types containing asthma-related concepts). However, semantic-level corpora were relatively homogeneous (topic similarity = 0.944, asthma-related concept similarity = 0.971). The NLP system for asthma ascertainment had an F-score of 0.937 at Mayo, and produced 0.813 (prototype) and 0.908 (refinement) when applied at SCH. DISCUSSION: The criteria for asthma ascertainment are largely dependent on asthma-related concepts. Therefore, we believe that semantic similarity is important to estimate NLP system portability. As the Mayo Clinic and SCH corpora were relatively homogeneous at a semantic level, the NLP system, developed at Mayo Clinic, was imported to SCH successfully with proper adjustments to deal with the intrinsic corpus heterogeneity.

Indexed as

asthmadocumentation variationelectronic medical recordsnatural language processingportability

Identifiers

PMID29202185
PMCPMC7378885

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.