Evidence map›Paper›PMID 29202122›Full record

ArticleInternational journal of reproductive biomedicine2017

Evaluation of vitamin D status and its correlation with oxidative stress markers in women with polycystic ovary syndrome.

Maryam Rahsepar, Soleiman Mahjoub, Sedigheh Esmaelzadeh, Maryam Kanafchian, Maryam Ghasemi

Open access · goldAbstract read

In one paragraph

Article in International journal of reproductive biomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it

0cells of the map it votes in

8citing papers in PubMed, 1 pooled it

2.1field-weighted citation impact, top 13% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

Prevalence of Common Gynecological Conditions in the Middle East: Systematic Review and Meta-Analysis.Frontiers in reproductive health · 2021
Pooled it
The KAT5-TSP-1 Axis Maintains Ovarian Redox Homeostasis and Is Impaired in Polycystic Ovary Syndrome.Reproductive sciences (Thousand Oaks, Calif.) · 2026
Article
A Comparative Study of Food Intake and Adipose Tissue Distribution in Saudi Women with Polycystic Ovarian Syndrome.Healthcare (Basel, Switzerland) · 2024
Article
Serum dipeptidyl peptidase-4 activity and progranulin level in polycystic ovary syndrome patients.Caspian journal of internal medicine · 2022
Article
Effect of weight loss on pregnancy outcomes, neuronal-reproductive-metabolic hormones and gene expression profiles in granulosa cells in obese infertile PCOS patients undergoing IVF-ET.Frontiers in endocrinology · 2022
Article
Long noncoding RNAs as a piece of polycystic ovary syndrome puzzle.Molecular biology reports · 2021
Review
Low Vitamin D Level in Saudi Women With Polycystic Ovary Syndrome.Frontiers in nutrition · 2021
Article
Association Between Sex Steroids and Oxidative Status with Vitamin D Levels in Follicular Fluid of Non-obese PCOS and Healthy Women.Journal of reproduction & infertility
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maryam RahseparStudent Research Committee, Babol University of Medical Sciences, Babol, Iran.

Soleiman MahjoubFatemeh Zahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran.

Sedigheh EsmaelzadehFatemeh Zahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran.

Maryam KanafchianStudent Research Committee, Babol University of Medical Sciences, Babol, Iran.

Maryam GhasemiFatemeh Zahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran.

Babol University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is little evidence about antioxidant properties of vitamin D. Recent studies suggest that oxidative stress may play a major role in the pathophysiology of polycystic ovary syndrome (PCOS), but the association of vitamin D with oxidative stress is still not known in PCOS.

objectiveThe goal of the present study was to evaluate the correlation between serum 25-hydroxy vitamin D and oxidative stress markers in PCOS group compared to control group. MATERIALS AND

methods60 PCOS women (20-40 yr old) and 90 healthy women as control group were participated in this case-control study. Fasting serum level of 25(OH) D, glucose, insulin, calcium, malondialdehyde (MDA), protein carbonyl (PC), also homeostasis model assessment for insulin resistance (HOMA-IR) and fasting glucose to insulin ratio (FGIR) were measured.

resultsIt was found that the mean of serum 25(OH)D was lower in the PCOS group (10.76±4.17) than in the control group (12.07±6.26) but this difference was not statistically significant (p=0.125). Fasting insulin, HOMA-IR and MDA were significantly higher in the PCOS patients as compared to the controls, whereas PC level did not differ for the two groups (p=0.156). No significant correlations were found between 25(OH)D levels and oxidative stress markers (MDA and PC).

conclusionThe findings indicated no significant differences in the serum 25(OH)D levels between the PCOS patients and the matched controls. Also, no correlation was found between the serum vitamin D levels and oxidative stress markers in both groups.

Indexed as

MalondialdehydeOxidative stressPolycystic ovary syndromeVitamin D

Identifiers

PMID29202122

PMCPMC5605855

OpenAlexW2740377670

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.