Evidence map›Paper›PMID 29202045›Full record

ArticlemSphere

Adaptation in a Fibronectin Binding Autolysin of

Tatum D Mortimer, Douglas S Annis, Mary B O'Neill, Lindsey L Bohr, Tracy M Smith, Hendrik N Poinar, Deane F Mosher, Caitlin S Pepperell

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. The Urinary Microbiome and Bladder Cancer.Life (Basel, Switzerland) · 2023
    Review
  3. Review
  4. The immune responses to differentFrontiers in immunology · 2022
    Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Tatum D MortimerDepartment of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-6255-690X
Douglas S AnnisDepartment of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Mary B O'NeillDepartment of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Lindsey L BohrDepartment of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Tracy M SmithDepartment of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Hendrik N PoinarMcMaster Ancient DNA Centre, Department of Anthropology, McMaster University, Hamilton, Ontario, Canada.
Deane F MosherDepartment of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Caitlin S PepperellDepartment of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-6324-1333
University of Wisconsin–Madison · USCanadian Institute for Advanced Research · CA

Funding

GRADUATE TRAINING IN MOLECULAR BIOSCIENCEST32GM007215 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HULL, CHRISTINA M · 1985 to 2018
$22.5M
Drifting to victory: resolving the paradox of M.tuberculosis evolutionR01AI113287 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI Caitlin S Pepperell · 2015 to 2026
$6.5M
NIAID NIH HHS R01 AI113287NIGMS NIH HHS T32 GM007215
6 · The paper itself

Abstract

Human-pathogenic bacteria are found in a variety of niches, including free-living, zoonotic, and microbiome environments. Identifying bacterial adaptations that enable invasive disease is an important means of gaining insight into the molecular basis of pathogenesis and understanding pathogen emergence.

Indexed as

adhesinsevolutionpositive selectionStaphylococcus saprophyticusurinary tract infection

Identifiers

PMID29202045
PMCPMC5705806
OpenAlexW2949221602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.