ArticleAlzheimer's & dementia (New York, N. Y.)2017
Speed of processing training results in lower risk of dementia.
Article in Alzheimer's & dementia (New York, N. Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00298558 (Trial of a Cognitive Intervention for Older Adults), which is not on this map. Cited by 88 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Trial of a Cognitive Intervention for Older Adults
Who cites it
88 citing papers in PubMed, 3 syntheses or guidelines pooled it, 159 citations in OpenAlex.
- Behaviour Change Techniques in Computerized Cognitive Training for Cognitively Healthy Older Adults: A Systematic Review.Neuropsychology review · 2023Pooled it
- Do nonpharmacological interventions prevent cognitive decline? a systematic review and meta-analysis.Translational psychiatry · 2020Pooled it
- The impact of behavioral interventions on cognitive function in healthy older adults: A systematic review.Ageing research reviews · 2019Pooled it
- A feasibility pilot study comparing tablets and smartphones for an app-based speed training program in older people: an open-label, randomized controlled PROBE trial.Cognitive processing · 2025Trial
- Cognitive and Neuropsychiatric Effects of 40 Hz tACS Simultaneously with Cognitive Exercises for Dementia: A Randomized, Crossover, Double-Blind, Sham-Controlled Study.Medicina (Kaunas, Lithuania) · 2025Trial
- A 2-Year Longitudinal Randomized Control Trial of Speed of Processing Cognitive Training in Aging Adults with HIV-Associated Neurocognitive Disorder: Results of the Think Fast Study.AIDS and behavior · 2024Trial
- Auditory Processing but Not Peripheral Hearing Differs Between Older Adults With and Without Mild Cognitive Impairment.American journal of audiology · 2024Trial
- Learning ratio performance on a brief visual learning and memory test moderates cognitive training gains in Double Decision task in healthy older adults.GeroScience · 2024Trial
- Cognitive Training for Reduction of Delirium in Patients Undergoing Cardiac Surgery: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Computerized Cognitive and Skills Training in Older People With Mild Cognitive Impairment: Using Ecological Momentary Assessment to Index Treatment-Related Changes in Real-World Performance of Technology-Dependent Functional Tasks.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024Trial
- A 2-year longitudinal randomized controlled trial examining the transfer of speed of processing training to secondary cognitive domains in middle-aged and older adults with HIV-associated neurocognitive disorder: Results of the think fast study.The Clinical neuropsychologist · 2024Trial
- The Preventing Alzheimer's with Cognitive Training (PACT) randomized clinical trial.Contemporary clinical trials · 2022Trial
- Is more always better? Dose effect in a multidomain intervention in older adults at risk of dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Trial
- Improvements in Cognitive Performance With Computerized Training in Older People With and Without Cognitive Impairment: Synergistic Effects of Skills-Focused and Cognitive-Focused Strategies.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022Trial
- Proximal improvement and higher-order resting state network change after multidomain cognitive training intervention in healthy older adults.GeroScience · 2022Trial
- Can Individualized-Targeted Computerized Cognitive Training Benefit Adults with HIV-Associated Neurocognitive Disorder? The Training on Purpose Study (TOPS).AIDS and behavior · 2021Trial
- Comparing Web-Based and Classroom-Based Memory Training for Older Adults: The ACTIVE Memory Works™ Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2020Trial
- A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills.Journal of visualized experiments : JoVE · 2020Trial
- Trial
- Speed-of-Processing Training in Assisted and Independent Living: A Randomized Controlled Trial.Journal of the American Geriatrics Society · 2018Trial
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 6 institutions in 1 country.
Funding
Abstract
introductionCognitive training improves cognitive performance and delays functional impairment, but its effects on dementia are not known. We examined whether three different types of cognitive training lowered the risk of dementia across 10 years of follow-up relative to control and if greater number of training sessions attended was associated with lower dementia risk.
methodsThe Advanced Cognitive Training in Vital Elderly (NCT00298558) study was a randomized controlled trial (N = 2802) among initially healthy older adults, which examined the efficacy of three cognitive training programs (memory, reasoning, or speed of processing) relative to a no-contact control condition. Up to 10 training sessions were delivered over 6 weeks with up to four sessions of booster training delivered at 11 months and a second set of up to four booster sessions at 35 months. Outcome assessments were taken immediately after intervention and at intervals over 10 years. Dementia was defined using a combination of interview- and performance-based methods.
resultsA total of 260 cases of dementia were identified during the follow-up. Speed training resulted in reduced risk of dementia (hazard ratio [HR] 0.71, 95% confidence interval [CI] 0.50-0.998, DISCUSSION: Initially, healthy older adults randomized to speed of processing cognitive training had a 29% reduction in their risk of dementia after 10 years of follow-up compared to the untreated control group.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.