Evidence map›Paper›PMID 29201897›Full record

ArticleBioMed research international2017

Combined Treatment with an Anticoagulant and a Vasodilator Prevents Steroid-Associated Osteonecrosis of Rabbit Femoral Heads by Improving Hypercoagulability.

Fang Cao, Ge Liu, Wei Wang, Benjie Wang, Xiaowei Wei, Faqiang Lu, Fan Yang, Kai Kang, Yongxuan Wang, Jiahui Yang and 2 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Osteonecrosis of the Femoral Head: Update Article.Revista brasileira de ortopedia · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. LPS-induced inflammation disorders bone modeling and remodeling by inhibiting angiogenesis and disordering osteogenesis in chickens.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2020
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Fang CaoDepartment of Biomedical Engineering, Faculty of Electronic Information and Electronical Engineering, Dalian University of Technology, Dalian 116024, China.ORCID 0000-0001-5684-8121
Ge LiuDepartment of Orthopaedic Laboratory, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China.
Wei WangDepartment of Orthopaedic Laboratory, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China.
Benjie WangDepartment of Orthopaedic Laboratory, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China.
Xiaowei WeiDepartment of Orthopaedic Laboratory, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China.
Faqiang LuDepartment of Orthopaedic Laboratory, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China.
Fan YangDepartment of Biomedical Engineering, Faculty of Electronic Information and Electronical Engineering, Dalian University of Technology, Dalian 116024, China.
Kai KangDepartment of Orthopaedic Laboratory, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China.
Yongxuan WangDepartment of Orthopaedic Laboratory, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China.
Jiahui YangDepartment of Orthopaedic Laboratory, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China.
Kairong QinDepartment of Biomedical Engineering, Faculty of Electronic Information and Electronical Engineering, Dalian University of Technology, Dalian 116024, China.
Dewei ZhaoDepartment of Biomedical Engineering, Faculty of Electronic Information and Electronical Engineering, Dalian University of Technology, Dalian 116024, China.ORCID 0000-0001-8611-0558
Affiliated Zhongshan Hospital of Dalian University · CNDalian University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Steroid-associated osteonecrosis of the femoral head remains a challenging problem in orthopedics worldwide. One pathomechanism is ischemia of the femoral head, as a result of thrombus formation and vasoconstriction. The present study investigates the effects of combination prevention with enoxaparin and EGb 761 on steroid-associated ONFH in rabbits. Rabbits were randomly divided into 5 groups (control group, model group, enoxaparin group, ginkgo group, and combination group). With the exception of the control group, the groups of rabbits were modeled with lipopolysaccharide and methylprednisolone acetate. Starting with modeling, the enoxaparin group and ginkgo group were injected with 1

Indexed as

AnimalsAnticoagulantsBone Morphogenetic Protein 2Disease Models, AnimalEnoxaparinFemur HeadFemur Head NecrosisGinkgo bilobaHumansLipopolysaccharidesOsteogenesisOsteonecrosisRabbitsSteroidsThrombosisVascular Endothelial Growth Factor AAnticoagulantsBone Morphogenetic Protein 2EnoxaparinLipopolysaccharidesSteroidsVascular Endothelial Growth Factor AVasodilator Agents

Identifiers

PMID29201897
PMCPMC5671671
OpenAlexW2766586671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.