Evidence map›Paper›PMID 29201859›Full record

ArticleFrontiers in cellular and infection microbiology2017

Predictable, Tunable Protein Production in

Kendal G Cooper, Audrey Chong, Tregei Starr, Ciaran E Finn, Olivia Steele-Mortimer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Regulator-derived growth and fitness costs ofbioRxiv : the preprint server for biology · 2026
    Article
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  6. σeLife · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kendal G CooperLaboratory of Bacteriology, Rocky Mountain Laboratories, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States.
Audrey ChongLaboratory of Bacteriology, Rocky Mountain Laboratories, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States.
Tregei StarrLaboratory of Bacteriology, Rocky Mountain Laboratories, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States.
Ciaran E FinnLaboratory of Bacteriology, Rocky Mountain Laboratories, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States.
Olivia Steele-MortimerLaboratory of Bacteriology, Rocky Mountain Laboratories, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States.
National Institutes of Health · USNational Institute of Allergy and Infectious Diseases · US

Funding

The Salmonella-Containing VacuoleZIAAI000909 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI STEELE-MORTIMER, OLIVIA · 2009 to 2025
$12.9M
Intramural NIH HHS ZIA AI000909
6 · The paper itself

Abstract

Here we describe the use of synthetic genetic elements to improve the predictability and tunability of episomal protein production in

Indexed as

Bacterial ProteinsCytosolDNA Copy Number VariationsGenes, BacterialGreen Fluorescent ProteinsHeLa CellsHost-Pathogen InteractionsHumansPlasmidsPromoter Regions, GeneticSalmonellaSalmonella entericaSalmonella InfectionsTrans-ActivatorsType III Secretion SystemsBacterial ProteinsGreen Fluorescent ProteinsHilA protein, SalmonellaSopB protein, SalmonellaSpi1 protein, SalmonellaTrans-ActivatorsType III Secretion Systemsfluorescent proteinintracellularplasmidpromoterSalmonellasynthetic biology

Identifiers

PMID29201859
PMCPMC5696353
OpenAlexW2768714899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.