Evidence map›Paper›PMID 29201668›Full record

ArticleJournal of reproduction & infertility

Efficacy of Intrauterine Injection of Granulocyte Colony Stimulating Factor (G-CSF) on Treatment of Unexplained Recurrent Miscarriage: A Pilot RCT Study.

Simin Zafardoust, Mohammad Mehdi Akhondi, Mohammad Reza Sadeghi, Afsaneh Mohammadzadeh, Atousa Karimi, Sheyda Jouhari, Soheila Ansaripour

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of reproduction & infertility. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 5 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 5 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  6. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Simin ZafardoustReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Mohammad Mehdi AkhondiReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Mohammad Reza SadeghiReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Afsaneh MohammadzadehReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Atousa KarimiReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Sheyda JouhariReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Soheila AnsaripourReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Biotechnology Research Center · IRAcademic Center for Education, Culture and Research · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndometrium undergoes several changes in structure and cellular composition during pregnancy. Granulocyte Colony-stimulating Factor (GCS-F) is an important cytokine with critical role in embryo implantation and pregnancy. The aim of the present study was to evaluate the impact of intrauterine injection of G-CSF in patients who suffer from unexplained recurrent miscarriage (RM).

methodsIn the present randomized clinical trial, a total of 68 patients were randomly allocated into two study groups including intrauterine G-CSF (n=23, 300

resultsNo significant differences were observed between the two study groups when the rates of chemical pregnancy (26.1%

conclusionIn our study, no significant difference was observed between the two study groups when the rates of chemical pregnancy, implantation, clinical pregnancy and abortion were compared.

Indexed as

Granulocyte colony-stimulating factorIntrauterine injectionRecurrent miscarriage

Identifiers

PMID29201668
PMCPMC5691254
OpenAlexW2766851617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.