Evidence map›Paper›PMID 29201643›Full record

ArticleNeuroImage. Clinical2018

Relationships between brain metabolite levels, functional connectivity, and negative mood in urologic chronic pelvic pain syndrome patients compared to controls: A MAPP research network study.

Daniel E Harper, Eric Ichesco, Andrew Schrepf, Megan Halvorson, Tudor Puiu, Daniel J Clauw, Richard E Harris, Steven E Harte, MAPP Research Network

Open access · goldAbstract read
In one paragraph

Article in NeuroImage. Clinical, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Daniel E HarperChronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA. Electronic address: harperd@med.umich.edu.
Eric IchescoChronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Andrew SchrepfChronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Megan HalvorsonChronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Tudor PuiuChronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Daniel J ClauwChronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Richard E HarrisChronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Steven E HarteChronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
MAPP Research NetworkChronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
University of Michigan · US

Funding

MAPP Research NetworkU01DK082316 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI LANDIS, J RICHARD · 2008 to 2018
$17.2M
University of Michigan MAPP Research Network Discovery SiteU01DK082345 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CLAUW, DANIEL J, CLEMENS, J. QUENTIN · 2008 to 2021
$9.7M
Limited Competition for Continuation of the MAPP-RN DCCU24DK082316 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI LANDIS, J RICHARD · 2019 to 2021
$4.9M
University of Michigan's TMJD and Orofacial Pain Interdisciplinary ConsortiumK12DE023574 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CLAUW, DANIEL J, KAPILA, SUNIL D · 2013 to 2017
$1.8M
Mechanistic Characterization of Pain in Temporomandibular Disorders: Does Pain Centralization Influence Responsiveness to Peripherally Targeted Treatments?K99DE026810 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HARPER, DANIEL ELLIOTT · 2017 to 2018
$236k
NIDCR NIH HHS K12 DE023574NIDCR NIH HHS K99 DE026810NIDDK NIH HHS U01 DK082316NIDDK NIH HHS U01 DK082345NIDDK NIH HHS U24 DK082316
6 · The paper itself

Abstract

Until recently, the predominant pathology of chronic pelvic pain conditions was thought to reside in the peripheral tissues. However, mounting evidence from neuroimaging studies suggests an important role of the central nervous system in the pathogenesis of these conditions. In the present cross-sectional study, proton magnetic resonance spectroscopy (

Indexed as

AdultBrainCholineChronic PainCross-Sectional StudiesEmotionsFemalegamma-Aminobutyric AcidHumansImage Interpretation, Computer-AssistedMiddle AgedPelvic PainProton Magnetic Resonance SpectroscopySyndromeYoung AdultCholinegamma-Aminobutyric AcidCentralized painCholineGamma aminobutyric acid (GABA)Interstitial cystitisMAPPProton magnetic resonance spectroscopy

Identifiers

PMID29201643
PMCPMC5702874
OpenAlexW2770735113

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.