ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2017
Toward Bioelectronic Medicine-Neuromodulation of Small Peripheral Nerves Using Flexible Neural Clip.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 96 citations in OpenAlex.
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- Implantable soft bladder-machine interface for neurogenic bladder dysfunction.Nature communications · 2026Article
- Recent Technological Advances in Monitoring and Neuromodulation of Non-Malignant and Neurogenic Bladder Conditions.Advanced healthcare materials · 2026Review
- A biodegradable capacitive-coupling neurostimulator for wireless electroceutical treatment of inflammatory bowel diseases.Science advances · 2025Article
- Soft-Actuated Cuff Electrodes with Minimal Contact for Bidirectional Peripheral Interfaces.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Bioelectronic Medicines-A Novel Approach of Therapeutics in Current Epoch.Current pharmaceutical design · 2025Review
- Highly-stable, injectable, conductive hydrogel for chronic neuromodulation.Nature communications · 2024Article
- Kirigami-Structured, Low-Impedance, and Skin-Conformal Electronics for Long-Term Biopotential Monitoring and Human-Machine Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Hybrid Bionic Nerve Interface for Application in Bionic Limbs.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Artificial intelligence enhanced sensors - enabling technologies to next-generation healthcare and biomedical platform.Bioelectronic medicine · 2023Review
- The effect of the subthreshold oscillation induced by the neurons' resonance upon the electrical stimulation-dependent instability.Frontiers in neuroscience · 2023Article
- Advanced Implantable Biomedical Devices Enabled by Triboelectric Nanogenerators.Nanomaterials (Basel, Switzerland) · 2022Review
- Research Progress on the Flexibility of an Implantable Neural Microelectrode.Micromachines · 2022Review
- A Microclip Peripheral Nerve Interface (μcPNI) for Bioelectronic Interfacing with Small Nerves.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation.Science translational medicine · 2021Article
- Lower urinary tract dysfunction in pediatrics progress to kidney disease in adolescents: Toward precision medicine in treatment.World journal of nephrology · 2021Review
- Advanced Neural Interface toward Bioelectronic Medicine Enabled by Micro-Patterned Shape Memory Polymer.Micromachines · 2021Article
- Wearable and Implantable Electroceuticals for Therapeutic Electrostimulations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Flourishing energy harvesters for future body sensor network: from single to multiple energy sources.iScience · 2021Review
- A Focused Review of Neural Recording and Stimulation Techniques With Immune-Modulatory Targets.Frontiers in immunology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neural modulation technology and the capability to affect organ function have spawned the new field of bioelectronic medicine. Therapeutic interventions depend on wireless bioelectronic neural interfaces that can conformally and easily attach to small (few hundred micrometers) nerves located deep in the body without neural damage. Besides size, factors like flexibility and compliance to attach and adapt to visceral nerves associated moving organs are of paramount importance and have not been previously addressed. This study proposes a novel flexible neural clip (FNC) that can be used to interface with a variety of different peripheral nerves. To illustrate the flexibility of the design, this study stimulates the pelvic nerve, the vagus nerve, and branches of the sciatic nerve and evaluates the feasibility of the design in modulating the function of each of these nerves. It is found that this FNC allows fine-tuning of physiological processes such as micturition, heart rate, and muscle contractions. Furthermore, this study also tests the ability of wirelessly powered FNC to enable remote modulation of visceral pelvic nerves located deep in the body. These results show that the FNC can be used with a range of different nerves, providing one of the critical pieces in the field of bioelectronics medicines.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.