Evidence map›Paper›PMID 29201591›Full record

ArticleNanophotonics (Berlin, Germany)2017

Optofluidic bioanalysis: fundamentals and applications.

Damla Ozcelik, Hong Cai, Kaelyn D Leake, Aaron R Hawkins, Holger Schmidt

Abstract read
In one paragraph

Article in Nanophotonics (Berlin, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. On-Chip Optical Detection of Viruses: A Review.Advanced photonics research · 2021
    Article
  6. Review
  7. Article
  8. Article
  9. High Trap Stiffness Microcylinders for Nanophotonic Trapping.ACS applied materials & interfaces · 2019
    Article
  10. Buried Rib SiOIEEE photonics technology letters : a publication of the IEEE Laser and Electro-optics Society · 2018
    Article
  11. Article
  12. Article
  13. Optofluidic Amplification-free Multiplex Detection of Viral Hemorrhagic Fevers.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
    Article
  14. Enhanced Detection of Single Viruses On-Chip via Hydrodynamic Focusing.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Damla OzcelikSchool of Engineering, University of California-Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA.
Hong CaiSchool of Engineering, University of California-Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA.
Kaelyn D LeakeSchool of Engineering, University of California-Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA.
Aaron R HawkinsECEn Department, 459 Clyde Building, Brigham Young University, Provo, UT 84602, USA.
Holger SchmidtSchool of Engineering, University of California-Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA.

Funding

Multiplexed, Non-Amplified, Nucleic Acid-Based Identification of Multidrug Resistant Pathogens Using an Integrated Optofluidic PlatformR01AI116989 · NIAID · BRIGHAM YOUNG UNIVERSITY · PI HAWKINS, AARON R., PITT, WILLIAM G · 2015 to 2019
$5.4M
Hybrid integrated molecular analysis (HIMAS) for point-of-care diagnosticsR33AI100229 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI SCHMIDT, HOLGER · 2014 to 2016
$1.7M
NIAID NIH HHS R01 AI116989NIAID NIH HHS R33 AI100229
6 · The paper itself

Abstract

Over the past decade, optofluidics has established itself as a new and dynamic research field for exciting developments at the interface of photonics, microfluidics, and the life sciences. The strong desire for developing miniaturized bioanalytic devices and instruments, in particular, has led to novel and powerful approaches to integrating optical elements and biological fluids on the same chip-scale system. Here, we review the state-of-the-art in optofluidic research with emphasis on applications in bioanalysis and a focus on waveguide-based approaches that represent the most advanced level of integration between optics and fluidics. We discuss recent work in photonically reconfigurable devices and various application areas. We show how optofluidic approaches have been pushing the performance limits in bioanalysis, e.g. in terms of sensitivity and portability, satisfying many of the key requirements for point-of-care devices. This illustrates how the requirements for bianalysis instruments are increasingly being met by the symbiotic integration of novel photonic capabilities in a miniaturized system.

Indexed as

biosensingintegrated opticslab-on-chipoptofluidicsphotonics

Identifiers

PMID29201591
PMCPMC5708574

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.