Evidence map›Paper›PMID 29201454›Full record

ReviewJournal of thoracic disease2017

The role of peptide receptor radionuclide therapy in advanced/metastatic thoracic neuroendocrine tumors.

Lisa Bodei, Jarosław B Ćwikla, Mark Kidd, Irvin M Modlin

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Modeling Lung Carcinoids with Zebrafish Tumor Xenograft.International journal of molecular sciences · 2022
    Article
  9. Article
  10. Kidney Protection with the Radical Scavenger αAntioxidants (Basel, Switzerland) · 2021
    Review
  11. Biomolecules · 2021
    Article
  12. Enhancing the anti-tumour activity ofScientific reports · 2020
    Article
  13. Current radiopharmaceuticals · 2020
    Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Lisa BodeiMolecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jarosław B ĆwiklaFaculty of Medical Sciences, University of Warmia and Mazury, Olsztyn, Poland.
Mark KiddWren Laboratories, Branford, CT, USA.
Irvin M ModlinDepartment of Surgery, Yale University School of Medicine, New Haven, CT, USA.
Memorial Sloan Kettering Cancer Center · USUniversity of Warmia and Mazury in Olsztyn · PLWren Laboratories (United States) · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchopulmonary (BP) neuroendocrine tumors (NETs) comprise a spectrum of tumors that develop from respiratory neuroendocrine cells and represent ~20% of all lung neoplasia and ~30% of all NETs. The only curative treatment is surgical resection. For well-differentiated forms (typical and atypical carcinoids), medical therapy ranges from bioactive agents (e.g., somatostatin analogs), to biotherapy (e.g., everolimus), standard chemotherapy and peptide receptor radionuclide therapy (PRRT). PRRT with radiolabeled somatostatin analogs is an innovative treatment for inoperable or metastasized, well/moderately differentiated, NET. Initially developed for gastroenteropancreatic tumors, it is also used in BP-NET because these tumors express the target receptor. Two decades of clinical trials with either

Indexed as

177Lu-octreotate90Y-octreotideBronchopulmonary (BP)neuroendocrine tumor (NET)peptide receptor radionuclide therapy (PRRT)

Identifiers

PMID29201454
PMCPMC5690948
OpenAlexW2767407969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.