Evidence map›Paper›PMID 29201417›Full record

ArticleContraception and reproductive medicine2017

Cancer survivors of gynecologic malignancies are at risk for decreased opportunity for fertility preservation.

Wael H Salem, Joe M Letourneau, Jessica Chan, Sai-Wing Chan, Marcelle Cedars, Mitchell P Rosen

Open access · goldAbstract read
In one paragraph

Article in Contraception and reproductive medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Ovarian Stimulation Is Safe and Effective for Patients with Gynecologic Cancer.Journal of adolescent and young adult oncology · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wael H SalemUniversity of California, San Francisco, Department of Obstetrics, Gynecology and Reproductive Sciences, San Francisco, CA USA.
Joe M LetourneauUniversity of California, San Francisco, Department of Obstetrics, Gynecology and Reproductive Sciences, San Francisco, CA USA.
Jessica ChanUniversity of California, San Francisco, Department of Obstetrics, Gynecology and Reproductive Sciences, San Francisco, CA USA.
Sai-Wing ChanUniversity of California, San Francisco, Department of Obstetrics, Gynecology and Reproductive Sciences, San Francisco, CA USA.
Marcelle CedarsUniversity of California, San Francisco, Department of Obstetrics, Gynecology and Reproductive Sciences, San Francisco, CA USA.
Mitchell P RosenUniversity of California, San Francisco, Department of Obstetrics, Gynecology and Reproductive Sciences, San Francisco, CA USA.
University of California, San Francisco · US

Funding

Clinical and Transtional Science InstituteTL1RR024129 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$2.0M
NCRR NIH HHS TL1 RR024129
6 · The paper itself

Abstract

backgroundCancer survivors rate fertility as one of the most important determinants of their quality of life in the years after cancer treatment. We seek to describe the reproductive goals of women affected by gynecologic cancers and investigate their specific challenges during fertility preservation (FP) counseling.

methodsUnivariate & multivariate logistic regression were used for quantitative analysis of objective FP counseling measures between women with gynecologic (GYN) and non-gynecologic (non-GYN) cancers from a cross sectional survey. Framework analysis was conducted on patient perception of physician-patient interactions.

resultsOf the 2537 women contacted, 1892 responded and 1686 reported treatment with potential to impact fertility. Among women with GYN cancers 52% wanted future children. Women <35 years were interested in FP (74%). Women with Gyn cancers received less FP counseling than women with non Gyn cancer (OR 0.5 95% CI 0.4-0.6). Three hundred twenty-four patients gave qualitative answers. Patient identified barriers included incomplete FP information (59%), nondisclosure (29%), a disinterest in FP (5%), and a perceived urgency to start treatment (7%).

conclusionsWomen with gynecologic cancers are less likely to be counseled about FP in comparison to women not affected by gynecologic cancers despite having similar fertility goals. We have identified patient perceived barriers to optimal FP counseling which may be improved upon to increase the value of FP and optimize quality of life for cancer survivors of gynecologic malignancies.

Indexed as

Cancer survivorshipCounselingFertility preservationGynecologic cancer

Identifiers

PMID29201417
PMCPMC5683589
OpenAlexW2583442619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.