Evidence map›Paper›PMID 29201357›Full record

ArticleBMC biophysics2017

Human S100A5 binds Ca

Lucas C Wheeler, Michael J Harms

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC biophysics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Evolution avoids a pathological stabilizing interaction in the immune protein S100A9.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lucas C WheelerDepartment of Chemistry and Biochemistry, University of Oregon, Eugene, 97403 OR USA.
Michael J HarmsDepartment of Chemistry and Biochemistry, University of Oregon, Eugene, 97403 OR USA.ORCID 0000-0002-0241-4122
Oregon Research Institute · US

Funding

MOLECULAR BIOLOGY AND BIOPHYSICST32GM007759 · NIGMS · UNIVERSITY OF OREGON · PI NOLEN, BRADLEY J · 1985 to 2021
$8.5M
Supplement to: Molecular mechanisms for the evolution of the total peptide binding set in S100 proteinsR01GM117140 · NIGMS · UNIVERSITY OF OREGON · PI HARMS, MICHAEL JONATHAN · 2016 to 2020
$1.6M
NIGMS NIH HHS R01 GM117140NIGMS NIH HHS T32 GM007759
6 · The paper itself

Abstract

backgroundS100A5 is a calcium binding protein found in a small subset of amniote tissues. Little is known about the biological roles of S100A5, but it may be involved in inflammation and olfactory signaling. Previous work indicated that S100A5 displays antagonism between binding of Ca

resultsWe found that human S100A5 is capable of binding both Cu

conclusionsS100A5 can bind Ca

Indexed as

AUCCalcium binding proteinsCircular dichroismCopper bindingITCS100A5S100 proteins

Identifiers

PMID29201357
PMCPMC5700546
OpenAlexW2768696710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.