ArticleClinical and translational allergy2017
Sensitization to PR-10 proteins is indicative of distinctive sensitization patterns in adults with a suspected food allergy.
Article in Clinical and translational allergy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
- Food Allergen Component Sensitization Patterns in Eosinophilic Esophagitis: Insights from a Retrospective Comparative Study.Foods (Basel, Switzerland) · 2026Article
- Revisiting Fruit Allergy: Prevalence across the Globe, Diagnosis, and Current Management.Foods (Basel, Switzerland) · 2023Review
- Novel, computational IgE-clustering in a population-based cross-sectional study: Mapping the allergy burden.Clinical and translational allergy · 2023Article
- Peanut Allergenicity: An Insight into Its Mitigation Using Thermomechanical Processing.Foods (Basel, Switzerland) · 2023Review
- Biochemical and clinical studies of putative allergens to assess what distinguishes them from other non-allergenic proteins in the same family.Transgenic research · 2022Article
- Prevalence of sensitization to molecular food allergens in Europe: A systematic review.Clinical and translational allergy · 2022Review
- Patterns of Clinical Reactivity in a Danish Cohort of Tree Nut Allergic Children, Adolescents, and Young Adults.Frontiers in allergy · 2022Article
- The Role of Lipid Transfer Proteins as Food and Pollen Allergens Outside the Mediterranean Area.Current allergy and asthma reports · 2021Review
- Ranking of 10 legumes according to the prevalence of sensitization as a parameter to characterize allergenic proteins.Toxicology reports · 2021Article
- Ligand Binding of PR-10 Proteins with a Particular Focus on the Bet v 1 Allergen Family.Current allergy and asthma reports · 2020Review
- Molecular approach to a patient's tailored diagnosis of the oral allergy syndrome.Clinical and translational allergy · 2020Review
- High-Yield Production of the Major Birch Pollen Allergen Bet v 1 With Allergen Immunogenicity inFrontiers in plant science · 2020Article
- Purification and Characterization of Pathogenesis Related Class 10 Panallergens.Foods (Basel, Switzerland) · 2019Article
- Allergy diagnosis from symptoms to molecules, or from molecules to symptoms: a comparative clinical study.The World Allergy Organization journal · 2018Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe extent of co-sensitization within and between food protein families in an adult population is largely unknown. This study aimed to identify the most frequently recognized components in the PR-10 and storage protein family, as well as patterns in (co-)sensitization, in a birch-endemic area.
methodsResults of ImmunoCAP ISAC, performed during routine care in Dutch adult outpatients suspected of food allergy, were collected.
resultsA total of 305 patients were selected, aged 16-79 years (median 32 years). Sensitization to one or more PR-10 proteins was most frequent (74% of all subjects), followed by 35% to storage protein and 15% to nsLTPs. Within the PR-10 family, subjects were most often sensitized to Bet v 1 (73% of 305), Cor a 1.04 (72%) and Mal d 1 (68%). Sensitization to PR-10s from soy, celery and kiwi occurred distinctively less often (< 55% of Bet v 1 sensitized subjects) compared to other food PR-10s (all > 70%). Subjects sensitized to these 'less common PR-10 proteins' were sensitized to more food and inhalant components on the ISAC, compared to subjects sensitized to 'common PR-10 proteins' (median 22 vs 13 out of 112,
conclusionsSensitization to PR-10 food proteins could occur without concomitant sensitization to common PR-10 from pollen in a subset of subjects. Less commonly recognized PR-10 proteins appear to be an indication of polysensitization.
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