ArticleCaspian journal of internal medicine2017
Nailfold capillaroscopy in 430 patients with rheumatoid arthritis.
Article in Caspian journal of internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- Dermatoscopic Assessment of Nail Fold Capillary Patterns in Patients of Color with Different Autoimmune Connective Tissue Diseases.Dermatology practical & conceptual · 2026Article
- Nailfold videocapillaroscopic changes in patients with psoriatic arthritis: A systematic review.Biomedical reports · 2025Article
- Abnormality detection in nailfold capillary images using deep learning with EfficientNet and cascade transfer learning.Scientific reports · 2025Article
- Non-Invasive Assessment of Micro- and Macrovascular Function after Initiation of JAK Inhibitors in Patients with Rheumatoid Arthritis.Diagnostics (Basel, Switzerland) · 2024Article
- "Scleroderma" and "Scleroderma-like" Capillaroscopic Pattern-Differences and Similarities.Current rheumatology reviews · 2024Article
- Microangiopathy in Rheumatic Diseases.Life (Basel, Switzerland) · 2023Article
- Study of Peripheral Microcirculation Assessed by Nailfold Video-Capillaroscopy and Association with Markers of Endothelial Dysfunction and Inflammation in Rheumatoid Arthritis.Mediterranean journal of rheumatology · 2022Article
- Nailfold Videocapillaroscopy for the Evaluation of Peripheral Microangiopathy in Rheumatoid Arthritis.Life (Basel, Switzerland) · 2022Review
- Capillary microscopy is a potential screening method for connective tissue disease in children with Raynaud's phenomenon.Pediatric rheumatology online journal · 2022Article
- Handheld dermatoscopy as an easy-to-use capillaroscopic instrument in rheumatoid arthritis: a cross-sectional studyTurkish journal of medical sciences · 2020Article
- Nailfold capillaroscopy and autoimmune connective tissue diseases in patients from a Portuguese nailfold capillaroscopy clinic.Rheumatology international · 2020Article
- Vascular acrosyndromes in young adult population. Definition of clinical symptoms and connections to joint hypermobility.Clinical rheumatology · 2019Observational
- Capillaroscopic features of microangiopathy in rheumatoid arthritis patients with peripheral vascular syndrome.Clinical rheumatology · 2019Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMicrovascular changes are one of the first obvious steps in numerous inflammatory diseases such as rheumatoid arthritis (RA). Nailfold video capillaroscopy (NFC) is an easy, reliable and safe method for evaluating peripheral microangiopathy. The objective of this study was to examine nailfold microcirculation in RA patients, assess morphological and structural changes quantitatively and qualitatively, and recognize useful changes.
methodsA total of 430 patients diagnosed with RA were examined in a period of 4 years. NFC was performed on all fingers of both hands in each patient. Different parameters indicating microvascular changes were detected and analyzed; such as microvascular architecture, capillary distribution disturbances, capillary morphology, capillary density, efferent/afferent limb ratio, subpapillary venular plexus and morphological abnormalities. The obtained results were categorized into normal pattern, nonspecific morphological abnormality and scleroderma pattern.
resultsThe mean age of participants was 51.03±14.54 (19-87 years) that consisted of 359 females and 71 males. Based on the findings, angiogenesis (74.7%) was the most pathological condition observed after tortuosity (99.5%). 7.2% and 20.9% of patients were categorized into normal and scleroderma pattern group, respectively. Among morphological abnormalities, angiogenesis, isolated enlarged loop, irregular enlarged loop and architectural derangement were significantly more frequent in scleroderma than normal pattern (p<0.001).
conclusionNFC may play an important role in monitoring RA disease and patients' follow-up. Therefore, in our opinion it could be considered in the course and follow-up of rheumatoid arthritis.
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