Evidence map›Paper›PMID 29201273›Full record

ArticleOxidative medicine and cellular longevity2017

Proinflammatory Cytokines Are Soluble Mediators Linked with Ventricular Arrhythmias and Contractile Dysfunction in a Rat Model of Metabolic Syndrome.

Evaristo Fernández-Sada, Alejandro Torres-Quintanilla, Christian Silva-Platas, Noemí García, B Cicero Willis, César Rodríguez-Rodríguez, Erasmo De la Peña, Judith Bernal-Ramírez, Niria Treviño-Saldaña, Yuriana Oropeza-Almazán and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Implications for neutrophils in cardiac arrhythmias.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  4. Article
  5. Article
  6. Immune Checkpoint Inhibitors Related to Cardiotoxicity.Journal of cardiovascular development and disease · 2022
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. COVID-19 and new-onset arrhythmia.Journal of arrhythmia · 2020
    Article
  14. Article
  15. Review
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Evaristo Fernández-SadaCátedra de Cardiología, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, Mexico.
Alejandro Torres-QuintanillaCátedra de Cardiología, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, Mexico.ORCID 0000-0002-7145-1840
Christian Silva-PlatasCátedra de Cardiología, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, Mexico.
Noemí GarcíaCátedra de Cardiología, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, Mexico.
B Cicero WillisCátedra de Cardiología, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, Mexico.ORCID 0000-0002-4984-6846
César Rodríguez-RodríguezCátedra de Cardiología, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, Mexico.
Erasmo De la PeñaCentro de Investigación Biomédica, Hospital Zambrano Hellion, Tec Salud del Sistema Tecnológico de Monterrey, Monterrey, Mexico.
Judith Bernal-RamírezCátedra de Cardiología, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, Mexico.
Niria Treviño-SaldañaCátedra de Cardiología, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, Mexico.ORCID 0000-0001-5824-7012
Yuriana Oropeza-AlmazánCátedra de Cardiología, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, Mexico.ORCID 0000-0003-0387-3686
Elena C CastilloCátedra de Cardiología, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, Mexico.ORCID 0000-0002-8799-8437
Leticia Elizondo-MontemayorCátedra de Cardiología, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, Mexico.ORCID 0000-0002-2076-1769
Karla CarvajalLaboratorio de Nutrición Experimental, Instituto Nacional de Pediatría, Ciudad de México, Mexico.ORCID 0000-0002-5522-3266
Gerardo García-RivasCátedra de Cardiología, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, Mexico.ORCID 0000-0003-4731-3293
Tecnológico de Monterrey · MXHospital Zambrano Hellion · MXInstituto Nacional de Pediatria · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic syndrome (MS) increases cardiovascular risk and is associated with cardiac dysfunction and arrhythmias, although the precise mechanisms are still under study. Chronic inflammation in MS has emerged as a possible cause of adverse cardiac events. Male Wistar rats fed with 30% sucrose in drinking water and standard chow for 25-27 weeks were compared to a control group. The MS group showed increased weight, visceral fat, blood pressure, and serum triglycerides. The most important increases in serum cytokines included IL-1

Indexed as

Adrenergic beta-AgonistsAnimalsArrhythmias, CardiacCells, CulturedCytokinesDisease Models, AnimalEchocardiographyHeartInterleukin-1betaIsoproterenolLeptinMaleMetabolic SyndromeMyocardial ContractionMyocardiumMyocytes, CardiacAdrenergic beta-AgonistsCytokinesInterleukin-1betaIsoproterenolLeptinTumor Necrosis Factor-alpha

Identifiers

PMID29201273
PMCPMC5671748
OpenAlexW2765445466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.