Evidence map›Paper›PMID 29201196›Full record

ArticleExperimental and therapeutic medicine2017

Lycium barbarum polysaccharide protects against neurotoxicity via the Nrf2-HO-1 pathway.

Shumei Cao, Jianlong Du, Qiaohong Hei

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
9.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Regulatory effects ofFrontiers in immunology · 2025
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  11. Article
  12. Antitumor Mechanisms ofLife (Basel, Switzerland) · 2024
    Review
  13. Article
  14. Review
  15. Characterization of Polysaccharides from the Pericarp ofMolecules (Basel, Switzerland) · 2023
    Article
  16. Review
  17. Oxidative medicine and cellular longevity · 2023
    Article
  18. Review
  19. Annals of medicine · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shumei CaoDepartment of Anesthesiology, Xi'an No. 1 Hospital, Xi'an, Shaanxi 710002, P.R. China.
Jianlong DuDepartment of Anesthesiology, No. 215 Hospital of Shaanxi Nuclear Industry, Xianyang, Shaanxi 712000, P.R. China.
Qiaohong HeiDepartment of Anesthesiology, Xi'an High-Tech Hospital, Xi'an, Shaanxi 710075, P.R. China.
Wuhan No.1 Hospital · CNXi'an High Tech University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of neurodegenerative diseases including Alzheimer's and Parkinson's disease has markedly increased over the past few decades. Oxidative stress is considered to be a common pathophysiological condition resulting in neurotoxicity. Lycium barbarum polysaccharide (LBP) is the major active component of Lycium barbarum L., which exhibit potent antioxidant activity. The current study investigated the neuroprotective effects of LBP in H

Indexed as

heme oxygenase-1Lycium barbarum polysaccharideneurotoxicitynuclear factor erythroid 2-related factor 2oxidative stress

Identifiers

PMID29201196
PMCPMC5704330
OpenAlexW2756217420

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.