Evidence map›Paper›PMID 29201176›Full record

ArticleExperimental and therapeutic medicine2017

Yunyi Yao, Jin-Zhong Huang, Liang Chen, Yingqi Chen, Xianhong Li

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Yunyi YaoDepartment of Biochemistry, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China.
Jin-Zhong HuangDepartment of Neurology, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu 213000, P.R. China.
Liang ChenDepartment of Pediatrics, Changhai Hospital, The Second Military Medical University, Shanghai 200433, P.R. China.
Yingqi ChenDepartment of Neurology, Suzhou Hospital of Traditional Chinese Medicine, Suzhou, Jiangsu 215009, P.R. China.
Xianhong LiDepartment of Neurology, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu 213000, P.R. China.
Soochow University · CNSecond Military Medical University · CNSuzhou Traditional Chinese Medicine Hospital · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a chronic neurodegenerative disease with an increasing morbidity rate. As one of the most important signaling pathways that responds to inflammation and degeneration, the p38 mitogen-activated protein kinase (MAPK) signaling pathway is active in the cortexes of AD mice. At the cellular level the same effect can be observed with p38 MAPK when induced by amyloid β (Aβ)

Indexed as

Alzheimer's diseaseamyloid β1–42apoptosisNADPH-cytochrome P450 reductasep38 mitogen-activated protein kinase

Identifiers

PMID29201176
PMCPMC5704317
OpenAlexW2759718069

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.