ReviewInternational journal of endocrinology and metabolism2017
Worldwide Recall Rate in Newborn Screening Programs for Congenital Hypothyroidism.
Review in International journal of endocrinology and metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Newborn screening for congenital hypothyroidism in France: a study of current professional practices.European thyroid journal · 2026Article
- Rapid peptide analysis in dried bloodspots to identify novel markers for newborn screening for congenital hypothyroidism.Scientific reports · 2026Article
- Enhancing TSH-based congenital hypothyroidism screening using machine learning and resampling algorithms.BMC medical informatics and decision making · 2025Article
- Implementation of Neonatal Screening Program for Congenital Hypothyroidism in Eastern Morocco.International journal of neonatal screening · 2025Article
- Neonatal Thyroid-Stimulating Hormone Reference Intervals in Multi-Ethnics Population.Children (Basel, Switzerland) · 2025Article
- Screening of 50,539 newborns for congenital hypothyroidism: optimization of TSH cut-off values and seasonal impact in clinical practice.Frontiers in endocrinology · 2025Article
- Impact of Lowering TSH Cut-Off on Neonatal Screening for Congenital Hypothyroidism in Minas Gerais, Brazil.International journal of neonatal screening · 2024Article
- Experiences and Challenges with Congenital Hypothyroidism Newborn Screening in Indonesia: A National Cross-Sectional Survey.International journal of neonatal screening · 2024Article
- Congenital hypothyroidism in India: A systematic review and meta-analysis of prevalence, screen positivity rates, and etiology.The Lancet regional health. Southeast Asia · 2022Article
- Co-designing Improved Communication of Newborn Bloodspot Screening Results to Parents: Mixed Methods Study.Journal of participatory medicine · 2022Article
- The Role of Iodine for Thyroid Function in Lactating Women and Infants.Endocrine reviews · 2022Review
- First Experiences with Newborn Screening for Congenital Hypothyroidism in Ulaanbaatar, Mongolia.International journal of neonatal screening · 2021Article
- Neonatal screening for congenital hypothyroidism in an Italian Centre: a 5-years real-life retrospective study.Italian journal of pediatrics · 2021Article
- A Novel Approach to Improve Newborn Screening for Congenital Hypothyroidism by Integrating Covariate-Adjusted Results of Different Tests into CLIR Customized Interpretive Tools.International journal of neonatal screening · 2021Article
- The Impact of Seasonal Changes on Thyroxine and Thyroid-Stimulating Hormone in Newborns.International journal of neonatal screening · 2021Article
- Familial-Related Risks for Congenital Hypothyroidism in Iranian Newborns: A Population-Based Case-Control Study.International journal of endocrinology and metabolism · 2021Article
- A Success Story: Review of the Implementation and Achievements of the National Newborn Screening Program for Congenital Hypothyroidism in Iran.International journal of endocrinology and metabolism · 2020Review
- Newborn Screening for Congenital Hypothyroidism, Congenital Adrenal Hyperplasia, and Glucose-6-Phosphate Dehydrogenase Deficiency for Improving Health Care in India.Journal of pediatric intensive care · 2020Article
- A global perspective on newborn congenital hypothyroidism screening.Proceedings (Baylor University. Medical Center) · 2020Article
- CONGENITAL HYPOTHYROIDISM SCREENING RESULTS IN THE TURKISH PROVINCE OF ADIYAMAN IN 2015-2020.Acta endocrinologica (Bucharest, Romania : 2005)Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextNeonatal mass screening program for congenital hypothyroidism provides the best tool for prevention of its devastating effects on mental development. Despite the overall success of the screening programs in detecting congenital hypothyroidism and eliminating its sequelae and new developments made in the program design, high recall rate and false positive results impose a great challenge worldwide. Lower recall rate and false positive results may properly organize project expenses by reducing the unnecessary repeated laboratory tests, increase physicians and parents' assurance and cooperation, as well as reduce the psychological effects in families. EVIDENCE ACQUISITION: In this review, we assessed the recall rate in different programs and its risk factors worldwide.
methodsPublications reporting the results of the CH screening program from 1997 to 2016 focusing on the recall rate have been searched.
resultsRecall rates vary from 0.01% to 13.3% in different programs; this wide range may be due to different protocols of screening (use of T4 or TSH or both), different laboratory techniques, site of sample collection, recall cutoff, iodine status, human error, and even CH incidence as affected by social, cultural, and regional factors of the population.
conclusionsIt is suggested to implement suitable interventions to reduce the contributing factors by improving the quality of laboratory tests, selecting conservative cut off points, control iodine deficiency, use of iodine free antiseptic during delivery, and use of more specific markers or molecular tests. Applying an age dependent criteria for thyrotropin levels can be helpful in regions with a varied time of discharge after delivery or for preterm babies.
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