ArticleStem cells international2017
Osteogenic Differentiation of hDPSCs on Biogenic Bone Apatite Thin Films.
Article in Stem cells international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- State of Art and Perspective of Calcium Phosphate-Based Coatings Coupled with Bioactive Compounds for Orthopedic Applications.Nanomaterials (Basel, Switzerland) · 2025Review
- Synthetic or Natural (Bio-Based) Hydroxyapatite? A Systematic Comparison between Biomimetic Nanostructured Coatings Produced by Ionized Jet Deposition.Nanomaterials (Basel, Switzerland) · 2024Article
- Ionized Jet Deposition of Calcium Phosphates-Based Nanocoatings: Tuning Coating Properties and Cell Behavior by Target Composition and Substrate Heating.Nanomaterials (Basel, Switzerland) · 2023Article
- Characterization of Dental Pulp Stem Cells Response to Bone Substitutes Biomaterials in Dentistry.Polymers · 2022Article
- Innovative Nanomaterials for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2022Article
- PEDOT: PSS promotes neurogenic commitment of neural crest-derived stem cells.Frontiers in physiology · 2022Article
- Role of ascorbic acid in the regulation of epigenetic processes induced by Porphyromonas gingivalis in endothelial-committed oral stem cells.Histochemistry and cell biology · 2021Article
- Evaluation of the In Vitro Biocompatibility of PEDOT:Nafion Coatings.Nanomaterials (Basel, Switzerland) · 2021Article
- Ionized jet deposition of antimicrobial and stem cell friendly silver-substituted tricalcium phosphate nanocoatings on titanium alloy.Bioactive materials · 2021Article
- Effects of the Sintering Process on Nacre-Derived Hydroxyapatite Scaffolds for Bone Engineering.Molecules (Basel, Switzerland) · 2020Article
- Regenerative potential of human dental pulp stem cells in the treatment of stress urinary incontinence: In vitro and in vivo study.Cell proliferation · 2019Article
- Bovine pericardium membrane, gingival stem cells, and ascorbic acid: a novel team in regenerative medicine.European journal of histochemistry : EJH · 2019Article
- Evaluation of Biological Response of STRO-1/c-Kit Enriched Human Dental Pulp Stem Cells to Titanium Surfaces Treated with Two Different Cleaning Systems.International journal of molecular sciences · 2019Article
- Optimized Surface Characteristics and Enhanced in Vivo Osseointegration of Alkali-Treated Titanium with Nanonetwork Structures.International journal of molecular sciences · 2019Article
- A Role for Exosomes in Craniofacial Tissue Engineering and Regeneration.Frontiers in physiology · 2019Review
- Cationic Substitutions in Hydroxyapatite: Current Status of the Derived Biofunctional Effects and Their In Vitro Interrogation Methods.Materials (Basel, Switzerland) · 2018Review
- Use of a 3D Floating Sphere Culture System to Maintain the Neural Crest-Related Properties of Human Dental Pulp Stem Cells.Frontiers in physiology · 2018Article
- Corrigendum to "Osteogenic Differentiation of hDPSCs on Biogenic Bone Apatite Thin Films".Stem cells international · 2017Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A previous study reported the structural characterization of biogenic apatite (BAp) thin films realized by a pulsed electron deposition system by ablation of deproteinized bovine bone. Thin films annealed at 400°C exhibited composition and crystallinity degree very close to those of biogenic apatite; this affinity is crucial for obtaining faster osseointegration compared to conventional, thick hydroxyapatite (HA) coatings, for both orthopedics and dentistry. Here, we investigated the adhesion, proliferation, and osteogenic differentiation of human dental pulp stem cells (hDPCS) on as-deposited and heat-treated BAp and stoichiometric HA. First, we showed that heat-treated BAp films can significantly promote hDPSC adhesion and proliferation. Moreover, hDPSCs, while initially maintaining the typical fibroblast-like morphology and stemness surface markers, later started expressing osteogenic markers such as Runx-2 and OSX. Noteworthy, when cultured in an osteogenic medium on annealed BAp films, hDPSCs were also able to reach a more mature and terminal commitment, with respect to HA and as-deposited films. Our findings suggest that annealed BAp films not only preserve the typical biological properties of stemness of, hDPSCs but also improve their ability of osteogenic commitment.
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Registered trials
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