ReviewDiabetes, metabolic syndrome and obesity : targets and therapy2017
Obesity and brain illness: from cognitive and psychological evidences to obesity paradox.
Review in Diabetes, metabolic syndrome and obesity : targets and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- Combined Lutein and Exercise Intervention Alleviates Brain Alteration Induced by a High-Fat Diet in Obese Rats.Food science & nutrition · 2026Article
- The Association Between Exercise and Cognitive Function in Chinese Middle-Aged and Older Adults: Exploration of Mediating Factors.Journal of sports science & medicine · 2025Article
- Endocrine and Metabolic Mechanisms Linking Obesity to Type 2 Diabetes: Implications for Targeted Therapy.Healthcare (Basel, Switzerland) · 2025Review
- Interplay between sex, age, BMI, health-related quality of life, and coping strategies in amateur and professional athletes.Frontiers in physiology · 2025Article
- How is the brain affected by metabolically healthy or unhealthy obesity in adulthood and elderly? A narrative review of neuroimaging and neurocognitive findings.Frontiers in aging neuroscience · 2025Review
- Goat Milk Supplementation Modulates the Mitochondrial Metabolic Flexibility and Orexin-A Levels Influencing the Inflammatory Pattern in Rats.Antioxidants (Basel, Switzerland) · 2024Article
- Longitudinal Examination of Body Mass Index and Cognitive Function in Older Adults: The HELIAD Study.Nutrients · 2023Article
- Relationship between Overweight/Obesity and Social Communication in Autism Spectrum Disorder Children: Mediating Effect of Gray Matter Volume.Brain sciences · 2023Article
- Association between Sedentary Behavior during Leisure Time and Excessive Weight in Chinese Children, Adolescents, and Adults.Nutrients · 2023Article
- Probiotics therapy show significant improvement in obesity and neurobehavioral disorders symptoms.Frontiers in cellular and infection microbiology · 2023Review
- The triglyceride glucose-waist-to-height ratio outperforms obesity and other triglyceride-related parameters in detecting prediabetes in normal-weight Qatari adults: A cross-sectional study.Frontiers in public health · 2023Article
- The Obesity Paradox: Effect of Body Mass Index and Waist Circumference on Post-Stroke Cognitive Impairment.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- The Cognitive Improvement and Alleviation of Brain Hypermetabolism Caused by FFAR3 Ablation in Tg2576 Mice Is Persistent under Diet-Induced Obesity.International journal of molecular sciences · 2022Article
- The Neglected Factor in the Relationship between Executive Functioning and Obesity: The Role of Motor Control.Healthcare (Basel, Switzerland) · 2022Article
- Factorial Model of Obese Adolescents: The Role of Body Image Concerns and Selective Depersonalization-A Pilot Study.International journal of environmental research and public health · 2022Article
- Abnormalities in deep-brain morphology and orbitofrontal cortical thinning relate to reward processing and body mass in adolescent girls.International journal of obesity (2005) · 2022Article
- Functional Relationship between Inhibitory Control, Cognitive Flexibility, Psychomotor Speed and Obesity.Brain sciences · 2022Article
- The Role of Nutraceutical Supplements, Monacolin K and Astaxanthin, and Diet in Blood Cholesterol Homeostasis in Patients with Myopathy.Biomolecules · 2022Observational
- Predicting the presence of depressive symptoms in the HIV-HCV co-infected population in Canada using supervised machine learning.BMC medical research methodology · 2022Article
- Physiological Role of Orexinergic System for Health.International journal of environmental research and public health · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent findings showed that obesity represents an additional risk factor to developing brain illness such as cognitive impairments and psychopathological disorders. However, some benefits of overweight in the elderly have been identified and an "obesity paradox" has been shown. Currently, it is still unknown how obesity and brain functioning could be linked, and the process by which body fat independently injures cognitive abilities and psychological well-being remains unclear. To establish the independent role of obesity on cognitive abilities and mental health, clarifying the role played by several factors and understanding their interaction is essential. In this review, we discuss the relationship between obesity and brain illness and underline the role played by confounders and other covariates to determine this link.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.