Evidence map›Paper›PMID 29200866›Full record

ReviewOncoTargets and therapy2017

The crossroads of breast cancer progression: insights into the modulation of major signaling pathways.

Fernando J Velloso, Arthur Fr Bianco, Jessica O Farias, Nadia Ec Torres, Pault Ym Ferruzo, Valesca Anschau, Henrique C Jesus-Ferreira, Ted Hung-Tse Chang, Mari Cleide Sogayar, Luiz F Zerbini and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in OncoTargets and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 86 citations in OpenAlex.

  1. Trial
  2. Article
  3. High uPAR and Low miR-221 Expression Predict Poor Disease-Free Survival in Triple-Negative Breast Cancer.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Anti‑proliferative effects ofOncology letters · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Sialyl LewisCancers · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 6 countries.

Fernando J Velloso *Cell and Molecular Therapy Center (NUCEL-NETCEM), School of Medicine.
Arthur Fr Bianco *Department of Pharmacology, Biomedical Sciences Institute.
Jessica O FariasDepartment of Biochemistry, Institute of Chemistry.
Nadia Ec TorresDepartament of Immunology, Biomedical Sciences Institute.
Pault Ym FerruzoDepartment of Biochemistry, Institute of Chemistry.
Valesca AnschauDepartment of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.
Henrique C Jesus-FerreiraCell and Molecular Therapy Center (NUCEL-NETCEM), School of Medicine.
Ted Hung-Tse ChangCancer Genomics Group, International Center for Genetic Engineering and Biotechnology (ICGEB), Cape Town, South Africa.
Mari Cleide SogayarCell and Molecular Therapy Center (NUCEL-NETCEM), School of Medicine.
Luiz F ZerbiniCancer Genomics Group, International Center for Genetic Engineering and Biotechnology (ICGEB), Cape Town, South Africa.
Ricardo G CorreaSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Cell Technology (China) · CNInternational Centre for Genetic Engineering and Biotechnology · ZADiscovery Institute · USInstitute of Biomedical Science · GBInstitute of Chemistry · CNInstitute of Immunology · HRSanford Burnham Prebys Medical Discovery Institute · USUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is the disease with highest public health impact in developed countries. Particularly, breast cancer has the highest incidence in women worldwide and the fifth highest mortality in the globe, imposing a significant social and economic burden to society. The disease has a complex heterogeneous etiology, being associated with several risk factors that range from lifestyle to age and family history. Breast cancer is usually classified according to the site of tumor occurrence and gene expression profiling. Although mutations in a few key genes, such as

Indexed as

breast cancerestrogen receptorJAK/STATMAPKNFκBPI3KTGFβWnt

Identifiers

PMID29200866
PMCPMC5701508
OpenAlexW2770595158

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.