Evidence map›Paper›PMID 29200734›Full record

ArticlePharmacognosy magazine

Toxicity and Detoxification Effects of Herbal

Yan Yan, Aihua Zhang, Hui Dong, Guangli Yan, Hui Sun, Xiuhong Wu, Ying Han, Xijun Wang

Open access · greenAbstract read
In one paragraph

Article in Pharmacognosy magazine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Safety of high-doseFood science & nutrition · 2021
    Article
  9. Article
  10. Review
  11. Review
  12. Toxicity and Its Mechanism Study ofEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
  13. Chemical Discrimination ofMolecules (Basel, Switzerland) · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yan YanSino-US Chinmedomics Technology Cooperation Center, National TCM Key Laboratory of Serum Pharmacochemistry, Research Center of Chinmedomics (State Administration of TCM), Laboratory of Metabolomics, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Aihua ZhangSino-US Chinmedomics Technology Cooperation Center, National TCM Key Laboratory of Serum Pharmacochemistry, Research Center of Chinmedomics (State Administration of TCM), Laboratory of Metabolomics, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Hui DongSino-US Chinmedomics Technology Cooperation Center, National TCM Key Laboratory of Serum Pharmacochemistry, Research Center of Chinmedomics (State Administration of TCM), Laboratory of Metabolomics, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Guangli YanSino-US Chinmedomics Technology Cooperation Center, National TCM Key Laboratory of Serum Pharmacochemistry, Research Center of Chinmedomics (State Administration of TCM), Laboratory of Metabolomics, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Hui SunSino-US Chinmedomics Technology Cooperation Center, National TCM Key Laboratory of Serum Pharmacochemistry, Research Center of Chinmedomics (State Administration of TCM), Laboratory of Metabolomics, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Xiuhong WuSino-US Chinmedomics Technology Cooperation Center, National TCM Key Laboratory of Serum Pharmacochemistry, Research Center of Chinmedomics (State Administration of TCM), Laboratory of Metabolomics, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Ying HanSino-US Chinmedomics Technology Cooperation Center, National TCM Key Laboratory of Serum Pharmacochemistry, Research Center of Chinmedomics (State Administration of TCM), Laboratory of Metabolomics, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Xijun WangSino-US Chinmedomics Technology Cooperation Center, National TCM Key Laboratory of Serum Pharmacochemistry, Research Center of Chinmedomics (State Administration of TCM), Laboratory of Metabolomics, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Heilongjiang University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMATERIALS AND

methodsMetabolomics was performed to identify the sensitive and reliable biomarkers and to characterize the phenotypically biochemical perturbations and potential mechanisms of CW-induced toxicity, and the detoxification by combinatorial intervention of CW with

resultsAs a result, the metabolites were characterized and responsible for pentose and glucuronate interconversions, tryptophan metabolism, amino sugar and nucleotide sugar metabolism, taurine and hypotaurine metabolism, fructose and mannose metabolism, and starch and sucrose metabolism, six networks of which were the same to the metabolic pathways of

conclusionMetabolomics analyses coupled with pattern recognition methods in the evaluation of drug toxicity and finding detoxification methods were highlighted in this work. SUMMARY: Metabolomics was performed to characterize the biochemical potential mechanisms of

Indexed as

Aconitumbiomarkersdetoxificationmass spectrometrymetabolomicstoxicitytraditional Chinese Medicine

Identifiers

PMID29200734
PMCPMC5701412
OpenAlexW2768673377

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.