ArticlePharmacognosy magazine
Superoxide Scavenging and Antiglycation Activity of Rhinacanthins-rich Extract Obtained from the Leaves of
Article in Pharmacognosy magazine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 25 citations in OpenAlex.
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- Ethnobotanical Survey on Bitter Tea in Taiwan.Frontiers in pharmacology · 2022Article
- Efficacy ofVeterinary world · 2021Article
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- An Ethnobotanical Study on Qīng-Căo-Chá Tea in Taiwan.Frontiers in pharmacology · 2020Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOxidative stress and nonenzymatic protein glycation lead to serious diabetic complications that increase the risk of mortality.
objectiveThe present study was performed to prepare a standardized rhinacanthins-rich extract (RRE) and evaluate its superoxide scavenging and antiglycation effects as compared to its marker compounds, namely, rhinacanthin-C (RC), rhinacanthin-D (RD), and rhinacanthin-N (RN). MATERIALS AND
methodsRRE was obtained by microwave-assisted green extraction along with a simple step of fractionation using Amberlite
resultsOn the basis of kinetic measurements, RRE exhibited the most potent antioxidant activity
conclusionsThe potent superoxide scavenging and albumin glycation inhibitory effect of RRE rationalized its therapeutic application in various chronic diseases, especially in the complications of diabetes. SUMMARY: Rhinacanthins-rich extract (RRE) exhibited potent superoxide scavenging activityRRE and rhinacanthin-C showed remarkable and comparable antiglycation effectRhinacanthins exhibited antiglycation activity by masking specific residues of albumin.
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