Evidence map›Paper›PMID 29200726›Full record

ArticlePharmacognosy magazine

Influence of Flavonoids on Mechanism of Modulation of Insulin Secretion.

Juliana Mikaelly Dias Soares, Ana Ediléia Barbosa Pereira Leal, Juliane Cabral Silva, Jackson R G S Almeida, Helinando Pequeno de Oliveira

Open access · greenAbstract read
In one paragraph

Article in Pharmacognosy magazine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Potential Effects of Sweet Potato (International journal of molecular sciences · 2021
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. (-)-Leucophyllone, a Tirucallane Triterpenoid fromPlants (Basel, Switzerland) · 2021
    Article
  11. Article
  12. Effects of Rutin on Wound Healing in Hyperglycemic Rats.Antioxidants (Basel, Switzerland) · 2020
    Article
  13. Constituents ofMolecules (Basel, Switzerland) · 2020
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Juliana Mikaelly Dias SoaresFederal University of Sao Francisco Valley, PE, Brazil.
Ana Ediléia Barbosa Pereira LealFederal University of Sao Francisco Valley, PE, Brazil.
Juliane Cabral SilvaDepartment of Physiology, Federal University of Sergipe, São Cristóvão, SE, Brazil.
Jackson R G S AlmeidaFederal University of Sao Francisco Valley, PE, Brazil.
Helinando Pequeno de OliveiraFederal University of Sao Francisco Valley, PE, Brazil.
Universidade Federal do Vale do São Francisco · BRUniversidade Federal de Sergipe · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe development of alternatives for insulin secretion control

objectiveTo study the influence of flavonoid on overall modulation mechanisms of insulin secretion.

methodsThe research was conducted in the following databases and platforms: PubMed, Scopus, ISI Web of Knowledge, SciELO, LILACS, and ScienceDirect, and the MeSH terms used for the search were flavonoids, flavones, islets of Langerhans, and insulin-secreting cells.

resultsTwelve articles were included and represent the basis of discussion on mechanisms of insulin secretion of flavonoids. Papers in ISI Web of Knowledge were in number of 1, Scopus 44, PubMed 264, ScienceDirect 511, and no papers from LILACS and SciELO databases.

conclusionAccording to the literature, the majority of flavonoid subclasses can modulate insulin secretion through several pathways, in an indication that corresponding molecule is a potential candidate for active materials to be applied in the treatment of diabetes. SUMMARY: The action of natural products on insulin secretion represents an important investigation topic due to their importance in the diabetes controlIn addition to their typical antioxidant properties, flavonoids contribute to the insulin secretionThe modulation of insulin secretion is induced by flavonoids according to different mechanisms.

Indexed as

Diabetesflavonesflavonoidsinsulininsulin-secreting cellsislets of Langerhans

Identifiers

PMID29200726
PMCPMC5701404
OpenAlexW2770305501

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.