ArticleIndian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology
Evaluation of Micronucleus in Exfoliated Buccal Epithelial Cells Using Liquid-based Cytology Preparation in Petrol Station Workers.
Article in Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 19 citations in OpenAlex.
- Association Between Genotoxic Effects of Ageing Dental Restorations and Micronuclei in Oral Mucosal Cells.Medicina (Kaunas, Lithuania) · 2025Article
- Artisanal Gem Mining in Brazil: A Source of Genotoxicity and Exposure to Toxic Elements.International journal of environmental research and public health · 2023Article
- Micronucleus and Its Significance in Effusion Fluids.Journal of cytologyArticle
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Authors and funding
5 authors at 1 institution in 1 country.
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Abstract
backgroundLiquid-based cytology (LBC) can be used for the evaluation of micronucleus (MN) in exfoliated buccal epithelial cells of populations occupationally exposed to potentially carcinogenic agents.
aimThis study was undertaken to evaluate the frequency of MN of exfoliated buccal epithelial cells using LBC preparation in petrol station workers. MATERIALS AND
methodsFifty petrol station workers (cases) and fifty hospital administrative staffs (controls) were recruited and evaluated for MN by May-Grunwald Giemsa, Hematoxylin and Eosin, and Papanicolaou stains using LBC preparation. Statistical analysis was performed with Student's
resultsRegardless of staining method used, the mean frequency of MN for cases was significantly higher than that of controls (
conclusionThe present study concluded that petrol station workers are under risk of significant cytogenetic damage. The MN in exfoliated buccal epithelial cells found to be a useful biomarker of occupational exposure to genotoxic chemicals. LBC can be used for sample preparation to evaluate the frequency of MN in those who are occupationally exposed to potentially carcinogenic agents in view of overall improvement on sample preservation and visualization of cell morphology.
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