ArticleHealth affairs (Project Hope)2017
Mortality Quadrupled Among Opioid-Driven Hospitalizations, Notably Within Lower-Income And Disabled White Populations.
Article in Health affairs (Project Hope), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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Who cites it
55 citing papers in PubMed, 105 citations in OpenAlex.
- Preventing Hospital Readmission for Patients With Comorbid Substance Use Disorder : A Randomized Trial.Annals of internal medicine · 2021Trial
- Regulating quasi-legal markets: Evidence from pain management clinic laws.Journal of public economics · 2025Article
- Health-related quality of life measures as predictors for recurrent hospitalization and mortality among patients in heroin-assisted treatment.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Maternal substance use disorder and neonatal health: epidemiologic and socioeconomic determinants in a case-control study, Shiraz, Iran.BMC pregnancy and childbirth · 2025Article
- Postoperative Opioid Prescribing Among Adults with Disabilities After a Medicare Opioid Limit Policy.Annals of surgery · 2025Article
- Identifying emergency department patients at high risk for opioid overdose using natural language processing and machine learning.Journal of substance use and addiction treatment · 2025Article
- Variability in trends of opioid-related hospital utilization among U.S. Adults, 2016-2021 check.EClinicalMedicine · 2025Article
- Association of Pharmacologic and Nonpharmacologic Management of Acute Low Back Pain with Overdose Hospitalizations: A Nested Case-Control Study.Journal of integrative and complementary medicine · 2025Article
- Using AI to screen for opioid use disorder.Nature medicine · 2025Article
- Independent and joint contributions of physical disability and chronic pain to incident opioid use disorder and opioid overdose among Medicaid patients.Psychological medicine · 2024Article
- Article
- Polysubstance use and post-discharge mortality risk among hospitalized patients with opioid use disorder.Preventive medicine reports · 2023Article
- Racial/ethnic disparities in timely receipt of buprenorphine among Medicare disability beneficiaries.Drug and alcohol dependence · 2023Article
- Trends in hospital admission related to poisoning by, narcotics and psychodysleptics and poisoning by antiepileptic, sedative-hypnotic, and antiparkinsonism drugs in England and Wales between April 1999 and April 2020: An ecological study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- Factors associated with hospitalizations for co-occurring HIV and opioid-related diagnoses: Evidence from the national inpatient sample, 2009-2017.Preventive medicine reports · 2023Article
- Non-overdose acute care hospitalizations for opioid use disorder among commercially-insured adults: a retrospective cohort study.Addiction science & clinical practice · 2023Article
- Buprenorphine After Nonfatal Opioid Overdose: Reduced Mortality Risk in Medicare Disability Beneficiaries.American journal of preventive medicine · 2023Article
- Disparities in postoperative opioid prescribing by race and ethnicity: an electronic health records-based observational study from Northern California, 2015-2020.Archives of public health = Archives belges de sante publique · 2023Article
- Quality of Opioid Use Disorder Treatment for Persons With and Without Disabling Conditions.JAMA network open · 2023Article
- The Association of Opioid Misuse and Suicidality among People with Disabilities.Substance use & misuse · 2023Article
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Authors and funding
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Abstract
Hospitals play an important role in caring for patients in the current opioid crisis, but data on the outcomes and composition of opioid-driven hospitalizations in the United States have been lacking. Nationally representative all-payer data for the period 1993-2014 from the National Inpatient Sample were used to compare the mortality rates and composition of hospitalizations with opioid-related primary diagnoses and those of hospitalizations for other drugs and for all other causes. Mortality among opioid-driven hospitalizations increased from 0.43 percent before 2000 to 2.02 percent in 2014, an average increase of 0.12 percentage points per year relative to the mortality of hospitalizations due to other drugs-which was unchanged. While the total volume of opioid-driven hospitalizations remained relatively stable, it shifted from diagnoses mostly involving opioid dependence or abuse to those centered on opioid or heroin poisoning (the latter have higher case fatality rates). After 2000, hospitalizations for opioid/heroin poisoning grew by 0.01 per 1,000 people per year, while hospitalizations for opioid dependence or abuse declined by 0.01 per 1,000 people per year. Patients admitted for opioid/heroin poisoning were more likely to be white, ages 50-64, Medicare beneficiaries with disabilities, and residents of lower-income areas. As the United States combats the opioid epidemic, efforts to help hospitals respond to the increasing severity of opioid intoxication are needed, especially in vulnerable populations.
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