Evidence map›Paper›PMID 29200190›Full record

ArticleJournal of occupational and environmental medicine2018

Libby Amphibole Disease: Pulmonary Function and CT Abnormalities in Vermiculite Miners.

Albert Miller, Jaime Szeinuk, Curtis W Noonan, Claudia I Henschke, Jean Pfau, Brad Black, David F Yankelevitz, Mingzhu Liang, Ying Liu, Rowena Yip and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of occupational and environmental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Albert MillerMount Sinai Health System, Icahn School of Medicine, New York, New York (Drs Miller, Henschke, Yankelevitz, Liang, Liu, Ms Yip, Ms Linker, Dr Flores); Northwell Health, Department of Occupational Medicine, Epidemiology and Prevention, Great Neck, New York (Dr Szeinuk); University of Montana, Missoula, Montana (Dr Noonan); Montana State University, Bozeman, Montana (Dr Pfau); and Center for Asbestos Related Disease, Libby, Montana (Dr Black, Ms McNew).
Jaime Szeinuk
Curtis W Noonan
Claudia I Henschke
Jean Pfau
Brad Black
David F Yankelevitz
Mingzhu Liang
Ying Liu
Rowena Yip
Tracy McNew
Laura Linker
Raja Flores
Universidad de Flores · AR

Funding

THE TISCH CANCER INSTITUTE - CANCER CENTER SUPPORT GRANTP30CA196521 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Deanna L Benson · 2015 to 2026
$35.4M
Libby Epidemiology Research ProgramR01TS000099 · TS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FLORES, RAJA M. · 2009 to 2013
$4.8M
ATSDR CDC HHS R01 TS000099NCI NIH HHS P30 CA196521
6 · The paper itself

Abstract

objectiveThis article describes radiologic and pulmonary function findings among miners exposed to Libby amphibole. Computed tomography (CT) permits the detection of the characteristic thin, lamellar pleural thickening (LPT).

methodsIndividuals who worked at the mine for a minimum of 6 months had chest CT and pulmonary function tests.

resultsPleural thickening was noted in 223 (87%) of the 256 miners, parenchymal abnormalities in 49 (19%). LPT, found in 151 (68%), was associated with low values of forced vital capacity and diffusion capacity and significantly lower values in all pulmonary function tests when associated with parenchymal abnormalities.

conclusionEighty-seven percent of miners exposed to Libby Amphibole had pleural abnormalities on CT. LPT alone, and more so with parenchymal abnormalities, resulted in decreased pulmonary function. The importance of this easily missed LPT is demonstrated by its high frequency and significant functional effects.

Indexed as

MiningAdultAgedAluminum SilicatesAsbestos, AmphiboleFemaleForced Expiratory VolumeHumansMaleMiddle AgedMontanaOccupational DiseasesOccupational ExposurePleuraPleural DiseasesPulmonary Diffusing CapacityAluminum SilicatesAsbestos, Amphibolevermiculite

Identifiers

PMID29200190
PMCPMC5805586
OpenAlexW2771104356

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.