ArticleeLife2017
A selective role for ventromedial subthalamic nucleus in inhibitory control.
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Hyperdirect insula-basal-ganglia pathway and adult-like maturity of global brain responses predict inhibitory control in children.Nature communications · 2019Pooled it
- Beyond the brake: The subthalamic nucleus predominantly facilitates action in non-human primates.Progress in neurobiology · 2026Article
- Distinct involvements of the subthalamic nucleus subpopulations in reward-biased decision-making in monkeys.eLife · 2026Article
- Neurons of the human subthalamic nucleus engage with local delta frequency processes during action cancellation.Nature communications · 2026Article
- Deep brain stimulation reduces subthalamic nucleus pathological dynamics and rescues gait deficits associated with dopamine loss.bioRxiv : the preprint server for biology · 2026Article
- Hierarchical binding of cognition to action in the human basal ganglia-thalamic circuit.bioRxiv : the preprint server for biology · 2026Article
- Subthalamic nucleus in patients with Parkinson's disease encodes changes and magnitude of applied force.NPJ Parkinson's disease · 2026Article
- Beyond the Brake: the Subthalamic Nucleus Predominantly Facilitates Action in Non-human Primates.bioRxiv : the preprint server for biology · 2025Article
- Distinct involvements of the subthalamic nucleus subpopulations in reward-biased decision-making in monkeys.bioRxiv : the preprint server for biology · 2025Article
- Regularized CCA identifies sex-specific brain-behavior associations in adolescent psychopathology.Translational psychiatry · 2025Article
- Global Motor System Suppression as the Primary Mechanism of Human Action Stopping: Challenging the Pause-Then-Cancel Model.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Similar Dynamic Frontal Cortex Representations of Auditory Stimuli Cueing Opposite Actions and Rewards.bioRxiv : the preprint server for biology · 2025Article
- Reliability of triggering the stop process is related to prefrontal-subthalamic hyperdirect pathway recruitment.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Subthalamic nucleus neurons encode syllable sequence and phonetic characteristics during speech.Journal of neurophysiology · 2024Article
- Article
- Movement-related increases in subthalamic activity optimize locomotion.Cell reports · 2024Article
- Subthalamic nucleus-language network connectivity predicts dopaminergic modulation of speech function in Parkinson's disease.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Subthalamic Activity for Motor Execution and Cancelation in Monkeys.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Architecture of the subthalamic nucleus.Communications biology · 2024Review
- Focused stimulation of dorsal versus ventral subthalamic nucleus enhances action-outcome learning in patients with Parkinson's disease.Brain communications · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The subthalamic nucleus (STN) is hypothesized to play a central role in the rapid stopping of movement in reaction to a stop signal. Single-unit recording evidence for such a role is sparse, however, and it remains uncertain how that role relates to the disparate functions described for anatomic subdivisions of the STN. Here we address that gap in knowledge using non-human primates and a task that distinguishes reactive and proactive action inhibition, switching and skeletomotor functions. We found that specific subsets of STN neurons have activity consistent with causal roles in reactive action stopping or switching. Importantly, these neurons were strictly segregated to a ventromedial region of STN. Neurons in other subdivisions encoded task dimensions such as movement
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.