Evidence map›Paper›PMID 29199391›Full record

ArticleEJNMMI physics2017

Variations in the practice of molecular radiotherapy and implementation of dosimetry: results from a European survey.

Katarina Sjögreen Gleisner, Emiliano Spezi, Pavel Solny, Pablo Minguez Gabina, Francesco Cicone, Caroline Stokke, Carlo Chiesa, Maria Paphiti, Boudewijn Brans, Mattias Sandström and 3 more

Open access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 87 citations in OpenAlex.

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  13. Cure of Micrometastatic B-Cell Lymphoma in a SCID Mouse Model UsingJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
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  14. Milestones in dosimetry for nuclear medicine therapy.The British journal of radiology · 2022
    Review
  15. Article
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  20. Dosimetry in Clinical Radiopharmaceutical Therapy of Cancer: Practicality Versus Perfection in Current Practice.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 13 institutions in 9 countries.

Katarina Sjögreen GleisnerDepartment of Medical Radiation Physics, Clinical Sciences Lund, Lund University, Lund, Sweden. katarina.sjogreen_gleisner@med.lu.se.ORCID http://orcid.org/0000-0001-5664-8760
Emiliano SpeziSchool of Engineering, Cardiff University, Cardiff, UK.
Pavel SolnyDepartment of Nuclear Medicine and Endocrinology, Motol University Hospital, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic.
Pablo Minguez GabinaDepartment of Medical Physics and Radiation Protection, Gurutzeta/Cruces University Hospital, Barakaldo, Spain.
Francesco CiconeNuclear Medicine, Sant'Andrea Hospital, Department of Surgical and Medical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy.
Caroline StokkeDepartment of Diagnostic Physics, Oslo University Hospital, Oslo, Norway.
Carlo ChiesaNuclear Medicine Division, Foundation IRCCS Istituto Nazionale Tumori, Milan, Italy.
Maria PaphitiDepartment of Medical Physics, Pammakaristos Hospital, Athens, Greece.
Boudewijn BransDepartment of Nuclear Medicine and PET Center, University Hospital, Ghent, Belgium.
Mattias SandströmDepartment of Surgical Sciences, Radiology, Uppsala University Hospital, Uppsala, Sweden.
Jill TippingThe Christie NHS Foundation Trust, Nuclear Medicine, Manchester, UK.
Mark KonijnenbergDepartment of Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Glenn FluxJoint Department of Physics, Royal Marsden Hospital and Institute of Cancer Research, Sutton, UK.
Cardiff University · GBCharles University · CZErasmus MC · NLFondazione IRCCS Istituto Nazionale dei Tumori · ITGhent University Hospital · BEHospital de Cruces · ESLund University · SEOslo University Hospital · NOPammakaristos Hospital · GRRoyal Marsden NHS Foundation Trust · GBSapienza University of Rome · ITThe Christie NHS Foundation Trust · GBUppsala University Hospital · SE

Funding

Cancer Research UK 16464
6 · The paper itself

Abstract

backgroundCurrently, the implementation of dosimetry in molecular radiotherapy (MRT) is not well investigated, and in view of the Council Directive (2013/59/Euratom), there is a need to understand the current availability of dosimetry-based MRT in clinical practice and research studies. The aim of this study was to assess the current practice of MRT and dosimetry across European countries.

methodsAn electronic questionnaire was distributed to European countries. This addressed 18 explicitly considered therapies, and for each therapy, a similar set of questions were included. Questions covered the number of patients and treatments during 2015, involvement of medical specialties and medical physicists, implementation of absorbed dose planning, post-therapy imaging and dosimetry, and the basis of therapy prescription.

resultsResponses were obtained from 26 countries and 208 hospitals, administering in total 42,853 treatments. The most common therapies were

conclusionsThere is a wide variation in MRT practice across Europe and for different therapies, including the extent of medical-physicist involvement and the implementation of dosimetry-guided treatments.

Indexed as

DosimetryEuropean surveyMolecular radiotherapyRadionuclide therapyRadiopharmaceutical therapy

Identifiers

PMID29199391
PMCPMC5712507
OpenAlexW2767946527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.