SynthesisJournal of musculoskeletal & neuronal interactions2017
Effect of weight bearing exercise to improve bone mineral density in children with cerebral palsy: a meta-analysis.
Synthesis in Journal of musculoskeletal & neuronal interactions, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- The effectiveness of optimal exercise-based strategy for patients with hip fracture: a systematic review and Bayesian network meta-analysis.Scientific reports · 2023Pooled it
- State of the Evidence Traffic Lights 2019: Systematic Review of Interventions for Preventing and Treating Children with Cerebral Palsy.Current neurology and neuroscience reports · 2020Pooled it
- High prevalence of low bone mineral density in wheelchair users regardless of sports participation: a cross-sectional analysis of the bonewheel study.European journal of applied physiology · 2026Article
- Physiotherapy-assisted overground exoskeleton use: mixed methods feasibility study protocol quantifying the user experience, as well as functional, neural, and muscular outcomes in children with mobility impairments.Frontiers in neuroscience · 2024Article
- The Role of Oxidative Stress in Multiple Exercise-Regulated Bone Homeostasis.Aging and disease · 2023Review
- Discordance in Bone Mineral Density between the Lumbar Spine and Femoral Neck Is Associated with Renal Dysfunction.Yonsei medical journal · 2022Article
- A Review on Recent Advances of Cerebral Palsy.Oxidative medicine and cellular longevity · 2022Review
- Bone Health in Childhood Chronic Disease.Endocrinology and metabolism clinics of North America · 2020Review
- Measurement of Bone Mineral Density in Children with Cerebral Palsy from an Ethical Issue to a Diagnostic Necessity.BioMed research international · 2020Article
- Recurrent femoral shaft fractures in a child with gnathodiaphyseal dysplasia: a case report.BMC musculoskeletal disorders · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite widespread clinical use of weight bearing exercises to manage low bone mineral density (BMD) in children and adolescents with cerebral palsy (CP), previous studies have reported heterogeneous results on the effect of weight bearing exercise on BMD. PURPOSE: We performed the current meta-analysis to assess the effects of weight bearing exercise on increasing BMD in children who have CP with low BMD. MATERIALS AND
methodsWe searched PubMed, Cochrane, and Embase from inception through to October 2016 for studies that aims to investigate the effect of weight bearing exercise on BMD in children with CP. Following the searching result, the 118 relevant studies were reviewed and undergone selection process. Standardized mean difference (SMD), 95% confidence intervals (CIs) and p-values were calculated for analysis.
resultsThree studies were ultimately included in the meta-analysis: one randomized-controlled study and two case-controlled studies. No significant difference was observed in the BMD of the lumbar spine between before treatment and after treatment (SMD,0.341; 95% CI,-0.647-1.330; p=0.449) but the BMD of the femur significantly improved after applying weight bearing exercise compared to pre-treatment values (SMD, 0.916; 95% CI, 0.382-1.114; p⟨0.001).
conclusionsWeight bearing exercise has a significant effect on improving BMD of the femur in children with CP.
Indexed as
Identifiers
29199195PMC5749042W2984029803What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.