Evidence map›Paper›PMID 29199130›Full record

ReviewComparative biochemistry and physiology. Toxicology & pharmacology : CBP2018

The neurological toxicity of heavy metals: A fish perspective.

Adrian J Green, Antonio Planchart

Abstract readReview
In one paragraph

Review in Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. The Behavioral Responses of Koi Carp (Animals : an open access journal from MDPI · 2025
    Article
  6. Lead Nitrate (Pb(NOMicroscopy research and technique · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Common and Trace Metals in Alzheimer's and Parkinson's Diseases.International journal of molecular sciences · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Influence of Humic Acids on the Removal of Arsenic and Antimony by Potassium Ferrate.International journal of environmental research and public health · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adrian J GreenGraduate Program in Toxicology, North Carolina State University, Raleigh, NC 27695, United States; Department of Biological Sciences, North Carolina State University, Raleigh, NC 27695, United States.
Antonio PlanchartGraduate Program in Toxicology, North Carolina State University, Raleigh, NC 27695, United States; Department of Biological Sciences, North Carolina State University, Raleigh, NC 27695, United States; Center for Human Health and the Environment, North Carolina State University, Raleigh, NC 27695, United States; W. M. Keck Center for Behavioral Biology, North Carolina State University, Raleigh, NC 27695, United States. Electronic address: ajplanch@ncsu.edu.

Funding

Translational Research Support CoreP30ES025128 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Andrew R. Binder · 2015 to 2026
$18.3M
TRAINING IN BIOCHEMICAL AND ENVIRONMENTAL TOXICOLOGYT32ES007046 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Seth William Kullman · 1985 to 2026
$5.1M
NIEHS NIH HHS P30 ES025128NIEHS NIH HHS T32 ES007046
6 · The paper itself

Abstract

The causes of neurodegenerative diseases are complex with likely contributions from genetic susceptibility and environmental exposures over an organism's lifetime. In this review, we examine the role that aquatic models, especially zebrafish, have played in the elucidation of mechanisms of heavy metal toxicity and nervous system function over the last decade. Focus is applied to cadmium, lead, and mercury as significant contributors to central nervous system morbidity, and the application of numerous transgenic zebrafish expressing fluorescent reporters in specific neuronal populations or brain regions enabling high-resolution neurodevelopmental and neurotoxicology research.

Indexed as

Nerve DegenerationZebrafishAnimalsAnimals, Genetically ModifiedBehavior, AnimalDisease Models, AnimalGene Expression Regulation, DevelopmentalHeavy Metal Poisoning, Nervous SystemHumansMetals, HeavyNervous SystemNeuronsRisk AssessmentWater Pollutants, ChemicalMetals, HeavyWater Pollutants, Chemical

Identifiers

PMID29199130
PMCPMC5936656

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.