Evidence map›Paper›PMID 29198996›Full record

ArticleJournal of diabetes and its complications2018

The relationship of health literacy to diabetes status differs by sex in older adults.

Michael Quartuccio, Eleanor M Simonsick, Susan Langan, Tamara Harris, Rebecca L Sudore, Roland Thorpe, Caterina Rosano, Felicia Hill-Briggs, Sherita Golden, Rita R Kalyani

Abstract read
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In one paragraph

Article in Journal of diabetes and its complications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. The Health, Aging, and Body Composition (Health ABC) Study-Ground-Breaking Science for 25 Years and Counting.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michael QuartuccioDivision of Endocrinology, Diabetes & Metabolism, The Johns Hopkins University, Baltimore, MD, United States.
Eleanor M SimonsickIntramural Research Program National Institute on Aging, Baltimore, MD, United States.
Susan LanganDivision of Endocrinology, Diabetes & Metabolism, The Johns Hopkins University, Baltimore, MD, United States.
Tamara HarrisIntramural Research Program National Institute on Aging, Baltimore, MD, United States.
Rebecca L SudoreDivision of Geriatrics, Department of Medicine, University of California, San Francisco, CA, United States; San Francisco Veterans Affairs Medical Center, San Francisco, CA, United States.
Roland ThorpeHopkins Center for Health Disparities Solution, The Johns Hopkins University, Baltimore, MD, United States.
Caterina RosanoDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States.
Felicia Hill-BriggsDivision of Endocrinology, Diabetes & Metabolism, The Johns Hopkins University, Baltimore, MD, United States; Division of General Internal Medicine, Johns Hopkins University, Baltimore, MD, United States; The Welch Center for Prevention, Epidemiology and Clinical Research, The Johns Hopkins University, Baltimore, MD, United States.
Sherita GoldenDivision of Endocrinology, Diabetes & Metabolism, The Johns Hopkins University, Baltimore, MD, United States; Division of General Internal Medicine, Johns Hopkins University, Baltimore, MD, United States; The Welch Center for Prevention, Epidemiology and Clinical Research, The Johns Hopkins University, Baltimore, MD, United States.
Rita R KalyaniDivision of Endocrinology, Diabetes & Metabolism, The Johns Hopkins University, Baltimore, MD, United States; The Welch Center for Prevention, Epidemiology and Clinical Research, The Johns Hopkins University, Baltimore, MD, United States. Electronic address: rrastogi@jhmi.edu.

Funding

VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Louise C. Walter · 2013 to 2026
$19.9M
Clinical Research&Epidemiology in Diabetes&EndocrinologyT32DK062707 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI TODD T BROWN, Wendy Lynet Bennett · 2002 to 2026
$7.3M
Health, Aging and Body Composition StudyZIAAG007390 · NIA · NATIONAL INSTITUTE ON AGING · PI LAUNER, LENORE J · 2009 to 2024
$4.0M
Mentoring Researchers in Advance Care Planning for Underrepresented Older Adults at Risk for Alzheimer’s Disease and Related Dementias and Their CaregiversK24AG054415 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI REBECCA L SUDORE · 2017 to 2026
$1.7M
Glucose Insulin and Muscle LossK23DK093583 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI KALYANI, RITA R · 2012 to 2015
$635k
Intramural NIH HHS ZIA AG007390NIA NIH HHS K24 AG054415NIA NIH HHS P30 AG044281NIDDK NIH HHS K23 DK093583NIDDK NIH HHS T32 DK062707
6 · The paper itself

Abstract

objectiveLower health literacy is associated with higher rates of mortality and chronic disease. It remains unclear whether health literacy is associated with diabetes and/or hyperglycemia in older adults, and if this relationship differs by sex. RESEARCH DESIGN AND

methodsWe performed a cross-sectional analysis of 2510 older adults in the Health, Aging and Body Composition (Health ABC) Study who had both a Rapid Estimate of Adult Literacy in Medicine (REALM) measurement and diabetes status available. Sex-stratified logistic regression models were used to analyze the relationship of health literacy categories (low, medium, and high) to diabetes status, adjusting for key covariates. Secondary analyses examined the relationship of health literacy to glycemic markers (A1C, fasting blood glucose).

resultsAmong participants in the Health ABC cohort, 429 had diabetes. Mean age was 76years old and 45% were female. Men with diabetes more commonly had low health literacy levels than men without diabetes (10.1% versus 9.3%, p=0.02). Similar results were seen among women (14.7% versus 6.1%, p<0.01). In a model adjusting for age, race, income, education, BMI, smoking, and alcohol use, women with low versus high health literacy had a two-fold higher likelihood of diabetes (OR=2.2; 95% CI 1.1-4.3). No significant relationship was observed in men. Progressively lower categories of health literacy were associated with higher age-adjusted mean A1C and fasting blood glucose levels in women (both p for trend <0.01) but not men.

conclusionsIn this large, ethnically diverse sample of community-dwelling older adults, lower health literacy level is related to a greater likelihood of diabetes and higher A1C and fasting blood glucose levels in women-but not in men-after adjusting for age, race, and other demographic and lifestyle factors. Future studies are needed to assess mechanisms underlying this relationship and if interventions to improve health literacy are effective in reducing the burden of diabetes, particularly in women.

Indexed as

AgedBlood GlucoseChronic DiseaseCross-Sectional StudiesDiabetes Mellitus, Type 2FemaleGlycated HemoglobinHealth LiteracyHealth StatusHumansHyperglycemiaMaleSelf CareSex FactorsBlood GlucoseGlycated HemoglobinDiabetes mellitusHealth literacyHyperglycemiaOlder adultsSex differences

Identifiers

PMID29198996
PMCPMC5849497

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.