Evidence map›Paper›PMID 29198587›Full record

ArticleThe Journal of allergy and clinical immunology2018

Bedroom allergen exposures in US households.

Päivi M Salo, Jesse Wilkerson, Kathryn M Rose, Richard D Cohn, Agustin Calatroni, Herman E Mitchell, Michelle L Sever, Peter J Gergen, Peter S Thorne, Darryl C Zeldin

Open access · greenAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Indoor allergen exposure in relation to sleep health among US adults.The journal of allergy and clinical immunology. Global · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Indoor Environmental Exposures and Their Relationship to Allergic Diseases.The journal of allergy and clinical immunology. In practice · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Home environment allergen exposure scale in older adult cohort with asthma.Canadian journal of public health = Revue canadienne de sante publique · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Päivi M SaloDivision of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC.
Jesse WilkersonSocial & Scientific Systems, Durham, NC.
Kathryn M RoseSocial & Scientific Systems, Durham, NC.
Richard D CohnSocial & Scientific Systems, Durham, NC.
Agustin CalatroniRho Federal Systems Division, Chapel Hill, NC.
Herman E MitchellRho Federal Systems Division, Chapel Hill, NC.
Michelle L SeverRho Federal Systems Division, Chapel Hill, NC.
Peter J GergenDivision of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Peter S ThorneUniversity of Iowa College of Public Health, Iowa City, Iowa.
Darryl C ZeldinDivision of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC. Electronic address: zeldin@niehs.nih.gov.
Rho (United States) · USSocial and Scientific Systems (United States) · USNational Institute of Environmental Health Sciences · USNational Institutes of Health · USUniversity of Iowa · US

Funding

Transplantation GroupUM2AI117870 · NIAID · RHO FEDERAL SYSTEMS DIVISION, INC. · PI DAVID, GLORIA · 2015 to 2023
$208.1M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5M
Indoor Allergens And AsthmaZIAES025041 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 2009 to 2025
$8.5M
INDOOR ALLERGENS AND ASTHMAZ01ES025041 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 1998 to 2008
$1.9M
Intramural NIH HHS Z01 ES025041NIAID NIH HHS UM2 AI117870NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

backgroundBedroom allergen exposures contribute to allergic disease morbidity because people spend considerable time in bedrooms, where they come into close contact with allergen reservoirs.

objectiveWe investigated participant and housing characteristics, including sociodemographic, regional, and climatic factors, associated with bedroom allergen exposures in a nationally representative sample of the US population.

methodsData were obtained from National Health and Nutrition Examination Survey 2005-2006. Information on participant and housing characteristics was collected by using questionnaires and environmental assessments. Concentrations of 8 indoor allergens (Alt a 1, Bla g 1, Can f 1, Fel d 1, Der f 1, Der p 1, Mus m 1, and Rat n 1) in dust vacuumed from nearly 7000 bedrooms were measured by using immunoassays. Exposure levels were classified as increased based on percentile (75th/90th) cutoffs. We estimated the burden of exposure to multiple allergens and used multivariable logistic regression to identify independent predictors for each allergen and household allergen burden.

resultsAlmost all participants (>99%) had at least 1 and 74.2% had 3 to 6 allergens detected. More than two thirds of participants (72.9%) had at least 1 allergen and 18.2% had 3 or more allergens exceeding increased levels. Although exposure variability showed significant racial/ethnic and regional differences, high exposure burden to multiple allergens was most consistently associated with the presence of pets and pests, living in mobile homes/trailers and older and rental homes, and living in nonmetropolitan areas.

conclusionsExposure to multiple allergens is common. Despite highly variable exposures, bedroom allergen burden is strongly associated with the presence of pets and pests.

Indexed as

AdolescentAir Pollution, IndoorAllergensAsthmaChildChild, PreschoolDustEnvironmental ExposureFemaleHousingHumansHypersensitivityInfantMaleNutrition SurveysAllergensDustAllergenallergyexposurehomeindoor

Identifiers

PMID29198587
PMCPMC5938098
OpenAlexW2775235946

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.