Evidence map›Paper›PMID 29198303›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2018

Predictors of Side Effects With Long-Term Oral Appliance Therapy for Obstructive Sleep Apnea.

Hitomi Ono Minagi, Kentaro Okuno, Kanji Nohara, Takayoshi Sakai

Abstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Comparison of side effects of different mandibular advancement devices for patients with obstructive sleep apnea: a systematic review and meta-analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Pooled it
  2. Dentoskeletal changes of long-term oral appliance treatment in patients with obstructive sleep apnea: A systematic review and meta-analysis.Journal of prosthodontics : official journal of the American College of Prosthodontists · 2025
    Pooled it
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  13. The role of oral appliance therapy in obstructive sleep apnoea.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
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  16. Article
  17. The effect of gradually increased mandibular advancement on the efficacy of an oral appliance in the treatment of obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Article
  18. Review
  19. Oral Appliances in Obstructive Sleep Apnea.Healthcare (Basel, Switzerland) · 2019
    Review
  20. More Than the Trajectory of the Teeth, We Need to Know About the Treatment Trajectory of Patients.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Hitomi Ono MinagiDepartment of Oral-facial Disorders, Osaka University Graduate School of Dentistry, Osaka, Japan.
Kentaro OkunoDepartment of Oral-facial Disorders, Osaka University Graduate School of Dentistry, Osaka, Japan.
Kanji NoharaDepartment of Oral-facial Disorders, Osaka University Graduate School of Dentistry, Osaka, Japan.
Takayoshi SakaiDepartment of Oral-facial Disorders, Osaka University Graduate School of Dentistry, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesThe aim of this study was to investigate the predictors of dental changes associated with long-term treatment with oral appliances (OAs) in patients with obstructive sleep apnea (OSA).

methodsThis was a retrospective study to investigate Japanese patients with OSA receiving long-term treatment with OAs. Comparisons of cephalometric analysis were carried out between the initial and follow-up assessments of dental and skeletal changes. Based on dental changes, predictors that may cause side effects were investigated.

resultsA total of 64 patients (average age at start of treatment: 57.7 ± 14.2 years, 44 males) were included in this study. The average duration of treatment was 4.3 ± 2.1 years. Over the total treatment period, there was a significant reduction in overjet (OJ) (1.5 ± 1.3 mm) and overbite (0.90 ± 1.5 mm), and an increase in the lower incisor line to the mandibular plane (3.1 ± 5.4°). A larger reduction in OJ of ≥ 1 mm was associated with treatment duration, use frequency, and mandibular advancement of the OAs. In addition to these predictive factors, the number of teeth was correlated with the amount of OJ reduction.

conclusionsFor long-term treatment with OAs, the risk of dental side effects should be considered, such as a reduction in OJ. A small number of maxillary teeth, as well as the factors associated with OAs, including treatment duration, use frequency, and mandibular advancement of the OAs, was correlated with an increased rate of OJ reduction. COMMENTARY: A commentary on this article appears in this issue on page 7.

Indexed as

CephalometryFemaleFollow-Up StudiesHumansJapanMaleMalocclusionMandibular AdvancementMiddle AgedRetrospective StudiesSleep Apnea, ObstructiveTimecephalometric analysisdental side effectslong-term treatmentmandibular advancement devicesoral appliancesleep apneasnoring

Identifiers

PMID29198303
PMCPMC5734880

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.