Evidence map›Paper›PMID 29198295›Full record

Trial reportJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2018

The Effect of Systematic Light Exposure on Sleep in a Mixed Group of Fatigued Cancer Survivors.

Lisa M Wu, Ali Amidi, Heiddis Valdimarsdottir, Sonia Ancoli-Israel, Lianqi Liu, Gary Winkel, Emily E Byrne, Ana Vallejo Sefair, Alejandro Vega, Katrin Bovbjerg and 1 more

2 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01873794 nacompletednot on this map

Treating Cancer-Related Fatigue Through Systematic Light Exposure

TypeinterventionalSponsorIcahn School of Medicine at Mount SinaiRan2012 to 2014Enrolled54ConditionsHematopoietic Stem Cell Transplantation, Breast Cancer, Fatigue, Mild Cognitive ImpairmentArmsBright white light, Dim red light
NCT04418856 nacompletednot on this mapstarted 2020, after this paper: background citation

Light Therapy to Treat Cancer-related Fatigue, Sleep Problems, Depression and Cognitive Impairment Among Breast Cancer Patients.

TypeinterventionalSponsorReykjavik UniversityRan2020 to 2024Enrolled260ConditionsBreast Cancer, Circadian Rhythms, Fatigue, Sleep DisturbanceArmsLight Glasses (Experimental), Light Glasses (Comparison)
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Effects of sleep interventions on cancer-related fatigue and quality of life in cancer patients: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
  3. Pooled it
  4. Trial
  5. Effects of chronotype-tailored bright light intervention on post-treatment symptoms and quality of life in breast cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Trial
  6. Trial
  7. Trial
  8. Trial
  9. Observational
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Lisa M WuDepartment of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
Ali AmidiUnit for Psychooncology and Health Psychology, Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.
Heiddis ValdimarsdottirDepartment of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
Sonia Ancoli-IsraelDepartment of Psychiatry, University of California, San Diego, California.
Lianqi LiuDepartment of Psychiatry, University of California, San Diego, California.
Gary WinkelDepartment of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
Emily E ByrneDepartment of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
Ana Vallejo SefairDepartment of Clinical and Social Psychology, University of Rochester, Rochester, New York.
Alejandro VegaDepartment of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
Katrin BovbjergDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
William H ReddDepartment of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
Icahn School of Medicine at Mount Sinai · USNorthwestern University · USUniversity of California San Diego · USAarhus University Hospital · DKReykjavík University · ISUniversity of Rochester · US

Funding

THE TISCH CANCER INSTITUTE - CANCER CENTER SUPPORT GRANTP30CA196521 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Ramon E Parsons · 2015 to 2026
$35.4M
Treating cognitive impairments in cancer patients via systematic light exposureK07CA184145 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WU, LISA MARIA · 2015 to 2019
$835k
NCI NIH HHS K07 CA184145NCI NIH HHS P30 CA196521
6 · The paper itself

Abstract

STUDY

objectivesSleep disturbances are commonly reported by cancer survivors. Systematic light exposure using bright light has been used to improve sleep in other populations. In this secondary data analysis, the effect of morning administration of bright light on sleep and sleep quality was examined in a mixed group of fatigued cancer survivors.

methodsForty-four cancer survivors screened for cancer-related fatigue were randomized to either a bright white light or a comparison dim red light condition. Participants were instructed to use a light box every morning for 30 minutes for 4 weeks. Wrist actigraphy and the Pittsburgh Sleep Quality Index were administered at 4 time points: prior to light treatment (baseline), 2 weeks into the intervention, during the last week of the intervention, and 3 weeks postintervention. Thirty-seven participants completed the end-of-intervention assessment.

resultsRepeated-measures linear mixed models indicated a statistically significant time × treatment group interaction effect with sleep efficiency improving more in the bright light condition over time compared with the dim light condition (

conclusionsThe results suggest that systematic bright light exposure in the morning may have beneficial effects on sleep in fatigued cancer survivors. Larger scale efficacy trials are warranted. CLINICAL

trial registrationRegistry: ClinicalTrials.gov, Title: Treating Cancer-Related Fatigue Through Systematic Light Exposure, Identifier: NCT01873794, URL: https://clinicaltrials.gov/ct2/show/NCT01873794.

Indexed as

ActigraphyCancer SurvivorsFatigueFemaleHumansMaleMiddle AgedNeoplasmsPhototherapySleepSleep Wake Disordersactigraphycancerfatiguelight therapysleep disturbancesleep efficiencysleep quality

Identifiers

PMID29198295
PMCPMC5734890
OpenAlexW2783852654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.