Evidence map›Paper›PMID 29198291›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2018

Adherence to Positive Airway Therapy After Switching From CPAP to ASV: A Big Data Analysis.

Jean-Louis Pépin, Holger Woehrle, Dongquan Liu, Shiyun Shao, Jeff P Armitstead, Peter A Cistulli, Adam V Benjafield, Atul Malhotra

2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05350332 narecruitingnot on this mapstarted 2022, after this paper: background citation

Characterizing the Effects of Lung Volume on Upper Airway Patency During Drug Induced Sleep Endoscopy in Patients With Obstructive Sleep Apnea

TypeinterventionalSponsorEmory UniversityRan2022 to 2027Enrolled151ConditionsObstructive Sleep ApneaArmsNegative Pressure Ventilator, Pulmonary Function Testing (PFT), Transcutaneous Phrenic Nerve Stimulation, Percutaneous Phrenic Nerve Stimulation
NCT07530302 narecruitingnot on this mapstarted 2026, after this paper: background citation

Treatment Failure of Continuous Positive Airway Pressure (CPAP) in Patients With Obstructive Sleep Apnea Syndrome (OSA): A Randomized Controlled Trial Comparing Polysomnography and the Sunrise Device to Drive Treatment-Adjustment Decisions.

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2026 to 2029Enrolled105ConditionsSleep Apnea Syndrome, ObstructiveArmsSunrise
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 92 citations in OpenAlex.

  1. Trial
  2. The importance of classifying central hypopneas: a call to action.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Review
  3. Article
  4. Article
  5. Evaluation of vestibular evoked myogenic potentials responses in patients with severe obstructive sleep apnea before and after continuous positive airway pressure therapy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Treatment-emergent central sleep apnea resolves with lower inspiratory pressure.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  10. Review
  11. Insights, recommendations, and research priorities for central sleep apnea: report from an expert panel.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  12. Article
  13. Article
  14. The Repeatability of Pharyngeal Opening Pressure Under Drug-Induced Sleep Endoscopy.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
    Article
  15. Article
  16. Article
  17. International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023
    Review
  18. CPAP setup by mail: we're not there yet.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  19. The Pathogenesis of Central and Complex Sleep Apnea.Current neurology and neuroscience reports · 2022
    Review
  20. A longitudinal study of the accuracy of positive airway pressure therapy machine-detected apnea-hypopnea events.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Jean-Louis PépinInstitut National de la Santé et de la Recherche Médicale (INSERM), HP2 Laboratory (Hypoxia: Pathophysiology), Grenoble Alpes University, Grenoble, France.
Holger WoehrleSleep and Ventilation Center Blaubeuren, Respiratory Center Ulm, Ulm, Germany.
Dongquan LiuResMed Asia Ltd, Singapore.
Shiyun ShaoResMed Asia Ltd, Singapore.
Jeff P ArmitsteadResMed Science Center, Sydney, Australia.
Peter A CistulliCharles Perkins Centre, University of Sydney, and Royal North Shore Hospital, Sydney, Australia.
Adam V BenjafieldResMed Science Center, ResMed Corp., San Diego, California.
Atul MalhotraUniversity of California San Diego, La Jolla, California.
ResMed (Australia) · AUInserm · FRResMed (United States) · USThe University of Sydney · AUUniversity of California San Diego · US

Funding

Single Motor Unit Genioglossus Recordings to Understand Sleep Apnea PathogenesisR01HL085188 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2008 to 2018
$3.5M
Training in the Next Generation in Respiratory ScienceT32HL134632 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, POWELL, FRANK L. · 2017 to 2021
$2.1M
Assessment of Upper Airway Mechanics Using Newer Electromyographic TechniquesK24HL132105 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2016 to 2020
$611k
NHLBI NIH HHS K24 HL132105NHLBI NIH HHS R01 HL085188NHLBI NIH HHS T32 HL134632
6 · The paper itself

Abstract

STUDY

objectivesThere is a lack of data regarding adherence trajectories when switching from continuous positive airway pressure (CPAP) to adaptive servoventilation (ASV) in the context of persistent or treatment-emergent central sleep apnea (CSA). This study investigated 90-day adherence rates in patients with sleep apnea based on the type of positive airway pressure (PAP) device used and any switching of PAP modality over time.

methodsTelemonitoring data were obtained from a United States PAP database. Eligible patients were a 30% random sample who started PAP, plus all who started ASV, from January 1, 2015 to October 2, 2015. All received PAP and had at least one session with usage of 1 hour or more. Adherence and device usage were determined in three groups: started on CPAP and stayed on CPAP (CPAP only); started on ASV and stayed on ASV (ASV only); started on CPAP, switched to ASV (Switch). The United States Medicare definition of adherence was used.

resultsThe study included 198,890 patients; 189,724 (CPAP only), 8,957 (ASV only) and 209 (Switch). In the Switch group, average apnea-hypopnea index decreased significantly on ASV versus CPAP. At 90 days, adherence rates were 73.8% and 73.2% in the CPAP only and ASV only groups. In the Switch group, CPAP adherence was 62.7%, improving to 76.6% after the switch to ASV. Mean device usage at 90 days was 5.27, 5.31, and 5.73 h/d in the CPAP only, ASV only, and Switch groups, respectively.

conclusionsTreatment-emergent or persistent CSA during CPAP reduced therapy adherence, but adherence improved early after switching from CPAP to ASV.

Indexed as

Big DataContinuous Positive Airway PressureFemaleHumansMaleMiddle AgedPatient CompliancePolysomnographyPositive-Pressure RespirationSleep Apnea, CentralUnited Statesadaptive servoventilationadherencecontinuous positive airway pressuresleep apnea

Identifiers

PMID29198291
PMCPMC5734894
OpenAlexW2783032176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.