ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2018
Direct genetic characterization of Toxoplasma gondii from clinical samples from Denmark: not only genotypes II and III.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- An African perspective on the genetic diversity ofParasitology · 2023Pooled it
- Identification of lineage-associated polymorphisms in the ROP18 3' flanking region and development of molecular assays for differentiation ofFrontiers in microbiology · 2026Article
- Review of Toxoplasmosis: What We Still Need to Do.Veterinary sciences · 2025Review
- Multiple Typing Approach to CharacterizeAnimals : an open access journal from MDPI · 2024Article
- The role of age in ocular toxoplasmosis: clinical signs of immunosenescence and inflammaging.Frontiers in medicine · 2024Article
- A ring trial to harmonize Toxoplasma gondii microsatellite typing: comparative analysis of results and recommendations for optimization.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023Article
- Spontaneous abortion among Toxoplasma gondii IgG seropositive women: Molecular detection, genotype identification, and serological assessment with conventional ELISA and avidity ELISA.The journal of obstetrics and gynaecology research · 2022Article
- Contamination of Soil, Water, Fresh Produce, and Bivalve Mollusks withMicroorganisms · 2022Review
- Review
- The disease burden of ocular toxoplasmosis in Denmark in 2019: Estimates based on laboratory testing of ocular samples and on publicly available register data.Parasite epidemiology and control · 2021Article
- A hotspot of Toxoplasma gondii Africa 1 lineage in Benin: How new genotypes from West Africa contribute to understand the parasite genetic diversity worldwide.PLoS neglected tropical diseases · 2021Article
- Parasites in the changing world - Ten timely examples from the Nordic-Baltic region.Parasite epidemiology and control · 2020Article
- White-tailed deer (Parasitology · 2020Article
- Genotyping of viableParasitology · 2020Article
- Is Real-Time PCR Targeting Rep 529 Suitable for Diagnosis of Toxoplasmosis in Patients Infected with Non-Type II Strains in North America?Journal of clinical microbiology · 2020Article
- A review of toxoplasmosis in humans and animals in Turkey.Parasitology · 2020Review
- Isolation, Genotyping, and Mouse Virulence Characterization ofFrontiers in veterinary science · 2020Article
- The prevalence of Toxoplasma gondii in mice living in Danish indoor sow herds.Acta veterinaria Scandinavica · 2019Article
- Toxoplasmosis in Germany.Deutsches Arzteblatt international · 2019Review
- Toxoplasma gondii seroprevalence in extensively farmed wild boars (Sus scrofa) in Denmark.Acta veterinaria Scandinavica · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic variation within Toxoplasma gondii can have both clinical and epidemiological significance, while the genotypes circulating in many parts of the world, including the Nordic country Denmark, are still unknown. We genetically characterized T. gondii strains that had been detected in human clinical samples in Denmark in 2011-2016. Samples that had tested positive for T. gondii DNA and had a quantification cycle value <33 were included in this study and subjected to direct genetic characterization of T. gondii based on length-polymorphism of 15 microsatellite markers. A total of 23 DNA samples from 22 individual patients were analyzed. The results were consistent with genotype II with 15/15 markers amplified from seven samples from the central nervous system (CNS) including two samples from one patient, four ocular samples, and one unspecified sample; with genotype III with 15/15 markers amplified from two ocular samples; with genotype Africa 1 with 15/15 markers amplified from one amniotic fluid sample and from one CNS-sample; with atypical genotype with 15/15 markers amplified from one CNS-sample and with 11/15 markers amplified from one CNS-sample; and with HG12-like genotype with 9/15 markers amplified from one CNS-sample. Genotype II, which is endemic in Europe, was predominant, but more than a third of the successfully genotyped strains were non-type-II. The possibility that clinical toxoplasmosis is caused by a strain that is not considered endemic to the region is definitely not negligible.
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