Evidence map›Paper›PMID 29197832›Full record

ArticleJournal of the American Heart Association2017

Comparison of Deep Sedation With General Anesthesia in Patients Undergoing Percutaneous Mitral Valve Repair.

Johannes Patzelt, Miriam Ulrich, Harry Magunia, Reinhard Sauter, Michal Droppa, Rezo Jorbenadze, Annika S Becker, Tobias Walker, Ralph Stephan von Bardeleben, Christian Grasshoff and 4 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Deep sedation versus general anaesthesia for transcatheter mitral valve repair: an individual patient data meta-analysis of observational studies.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Johannes PatzeltDepartment of Cardiology and Cardiovascular Medicine, University Hospital Eberhard Karls University Tuebingen, Tuebingen, Germany.
Miriam UlrichDepartment of Cardiology and Cardiovascular Medicine, University Hospital Eberhard Karls University Tuebingen, Tuebingen, Germany.
Harry MaguniaDepartment of Anesthesiology, University Hospital Eberhard Karls University Tuebingen, Tuebingen, Germany.
Reinhard SauterDepartment of Cardiology and Cardiovascular Medicine, University Hospital Eberhard Karls University Tuebingen, Tuebingen, Germany.
Michal DroppaDepartment of Cardiology and Cardiovascular Medicine, University Hospital Eberhard Karls University Tuebingen, Tuebingen, Germany.
Rezo JorbenadzeDepartment of Cardiology and Cardiovascular Medicine, University Hospital Eberhard Karls University Tuebingen, Tuebingen, Germany.
Annika S BeckerDepartment of Cardiology and Cardiovascular Medicine, University Hospital Eberhard Karls University Tuebingen, Tuebingen, Germany.
Tobias WalkerDepartment of Cardiovascular Surgery, University Hospital Eberhard Karls University Tuebingen, Tuebingen, Germany.
Ralph Stephan von BardelebenDepartment of Cardiology, University Hospital Johannes Gutenberg-University Mainz, Mainz, Germany.
Christian GrasshoffDepartment of Anesthesiology, University Hospital Eberhard Karls University Tuebingen, Tuebingen, Germany.
Peter RosenbergerDepartment of Anesthesiology, University Hospital Eberhard Karls University Tuebingen, Tuebingen, Germany.
Meinrad GawazDepartment of Cardiology and Cardiovascular Medicine, University Hospital Eberhard Karls University Tuebingen, Tuebingen, Germany.
Peter SeizerDepartment of Cardiology and Cardiovascular Medicine, University Hospital Eberhard Karls University Tuebingen, Tuebingen, Germany harald.langer@med.uni-tuebingen.de peter.seizer@med.uni-tuebingen.de.
Harald F LangerDepartment of Cardiology and Cardiovascular Medicine, University Hospital Eberhard Karls University Tuebingen, Tuebingen, Germany harald.langer@med.uni-tuebingen.de peter.seizer@med.uni-tuebingen.de.
University of Tübingen · DEJohannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous edge-to-edge mitral valve repair (PMVR) has become an established treatment option for mitral regurgitation in patients not eligible for surgical repair. Currently, most procedures are performed under general anesthesia (GA). An increasing number of centers, however, are performing the procedure under deep sedation (DS). Here, we compared patients undergoing PMVR with GA or DS. METHODS AND

resultsA total of 271 consecutive patients underwent PMVR at our institution between May 2014 and December 2016. Seventy-two procedures were performed under GA and 199 procedures under DS. We observed that in the DS group, doses of propofol (743±228 mg for GA versus 369±230 mg for DS,

conclusionsDS for PMVR is safe and feasible. No disadvantages with respect to procedural outcome or complications in comparison to GA were observed. Applying DS may simplify the PMVR procedure.

Indexed as

Anesthesia, GeneralCardiac CatheterizationDeep SedationAgedAged, 80 and overAnesthetics, IntravenousEchocardiography, Three-DimensionalEchocardiography, TransesophagealExercise ToleranceFeasibility StudiesFemaleHumansHypnotics and SedativesLength of StayMaleMiddle AgedAnesthetics, IntravenousHypnotics and SedativesNorepinephrinePropofolVasoconstrictor Agentsanesthesiamitral regurgitationpercutaneous mitral valve repair

Identifiers

PMID29197832
PMCPMC5779052
OpenAlexW2774934441

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.