Trial reportJournal of the American Heart Association2017
Association of Accelerometry-Measured Physical Activity and Cardiovascular Events in Mobility-Limited Older Adults: The LIFE (Lifestyle Interventions and Independence for Elders) Study.
Trial report in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 31 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The LIFE Study - Lifestyle Interventions and Independence for Elders
Development of a Tele-Physiotherapy Tool for the Early Management of Muskuloskeletal Pain in People With Visual Impairement (TeleEDxPhysio)
Who cites it
31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- A systematic review and meta-analysis of the long-term effects of physical activity interventions on objectively measured outcomes.BMC public health · 2023Pooled it
- Prospective Association of Daily Steps With Cardiovascular Disease: A Harmonized Meta-Analysis.Circulation · 2023Pooled it
- Daily Step Count and All-Cause Mortality: A Dose-Response Meta-analysis of Prospective Cohort Studies.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- The relationships between step count and all-cause mortality and cardiovascular events: A dose-response meta-analysis.Journal of sport and health science · 2021Pooled it
- Systematic review of the prospective association of daily step counts with risk of mortality, cardiovascular disease, and dysglycemia.The international journal of behavioral nutrition and physical activity · 2020Pooled it
- Feasibility of unsupervised, home-based leg heat therapy in older adults: a pilot, sham-controlled trial.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Trial
- Counseling Intervention and Cardiovascular Events in People With Peripheral Artery Disease: A Post Hoc Analysis of the BIP Randomized Clinical Trial.JAMA surgery · 2024Trial
- Trial
- Wearable Technology To Reduce Sedentary Behavior And CVD Risk In Older Adults: A Pilot Randomized Clinical Trial.Clinical interventions in aging · 2019Trial
- Digital Phenotyping in Health Research: Scoping Review of Methods, Gaps, and Opportunities.Journal of medical Internet research · 2026Article
- Wearable devices and cardiovascular health: revolutionizing remote monitoring and disease prevention.European heart journal · 2026Review
- Relationship Between Activity Tracker Metrics and the Physical Activity Index and Their Association With Cardiometabolic Phenotypes, Subclinical Atherosclerosis, and Cardiac Remodeling: Cross-Sectional Study.JMIR mHealth and uHealth · 2025Article
- Healthy ageing in older adults with cardiovascular disease.European heart journal · 2025Review
- Data Analytics in Physical Activity Studies With Accelerometers: Scoping Review.Journal of medical Internet research · 2024Article
- A social media game to increase physical activity among older adult women: protocol of a randomized controlled trial to evaluate CHALLENGE.BMC public health · 2024Article
- COVID-19: Insights into long-term manifestations and lockdown impacts.Journal of sport and health science · 2023Review
- The piety of optimization: The rhetoric of health awareness in ParticipACTION and Fitbit.Health (London, England : 1997) · 2023Article
- Effect of physical activity on the change in carotid intima-media thickness: An 8-year prospective cohort study.PloS one · 2023Article
- Exercise training maintains cardiovascular health: signaling pathways involved and potential therapeutics.Signal transduction and targeted therapy · 2022Review
- Validation of Corrected and Dispersed QT as Predictors of Adverse Outcomes in Acute Cardiotoxicities.Cardiovascular toxicology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 10 institutions in 1 country.
Funding
Abstract
backgroundData are sparse regarding the value of physical activity (PA) surveillance among older adults-particularly among those with mobility limitations. The objective of this study was to examine longitudinal associations between objectively measured daily PA and the incidence of cardiovascular events among older adults in the LIFE (Lifestyle Interventions and Independence for Elders) study. METHODS AND
resultsCardiovascular events were adjudicated based on medical records review, and cardiovascular risk factors were controlled for in the analysis. Home-based activity data were collected by hip-worn accelerometers at baseline and at 6, 12, and 24 months postrandomization to either a physical activity or health education intervention. LIFE study participants (n=1590; age 78.9±5.2 [SD] years; 67.2% women) at baseline had an 11% lower incidence of experiencing a subsequent cardiovascular event per 500 steps taken per day based on activity data (hazard ratio, 0.89; 95% confidence interval, 0.84-0.96;
conclusionsObjective measurements of physical activity via accelerometry were associated with cardiovascular events among older adults with limited mobility (summary score >10 on the Short Physical Performance Battery) both using baseline and longitudinal data. CLINICAL
trial registrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT01072500.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.