Evidence map›Paper›PMID 29197176›Full record

ArticleJournal of biomedical optics2017

Toward real-time diffuse optical tomography: accelerating light propagation modeling employing parallel computing on GPU and CPU.

Matthaios Doulgerakis, Adam Eggebrecht, Stanislaw Wojtkiewicz, Joseph Culver, Hamid Dehghani

Open access · goldAbstract read
In one paragraph

Article in Journal of biomedical optics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Matthaios DoulgerakisUniversity of Birmingham, School of Computer Science, Birmingham, United Kingdom.
Adam EggebrechtWashington University School of Medicine, Department of Radiology, St. Louis, Missouri, United States.
Stanislaw WojtkiewiczUniversity of Birmingham, School of Computer Science, Birmingham, United Kingdom.
Joseph CulverWashington University School of Medicine, Department of Radiology, St. Louis, Missouri, United States.
Hamid DehghaniUniversity of Birmingham, School of Computer Science, Birmingham, United Kingdom.
University of Birmingham · GBMallinckrodt (United States) · USWashington University in St. Louis · US

Funding

High-Sensitivity DOT for Mapping Human Brain FunctionR01NS090874 · NINDS · WASHINGTON UNIVERSITY · PI CULVER, JOSEPH P · 2014 to 2025
$5.5M
MAPPING FUNCTIONAL CONNECTIVITY WITH FLUORESCENCE MOLECULAR TOMOGRAPHYR01NS099429 · NINDS · WASHINGTON UNIVERSITY · PI CULVER, JOSEPH P · 2017 to 2021
$2.9M
NIRFASTR01CA132750 · NCI · DARTMOUTH COLLEGE · PI POGUE, BRIAN WILLIAM · 2009 to 2012
$1.2M
IMAGING BRAIN FUNCTION IN CHILDREN WITH AUTISM SPECTRUM DISORDERS WITH DIFFUSE OPTICAL TOMOGRAPHYK01MH103594 · NIMH · WASHINGTON UNIVERSITY · PI EGGEBRECHT, ADAM THOMAS · 2015 to 2019
$708k
Mapping Language Processing in Children with Autism Spectrum Disorder with Diffuse Optical TomographyR21MH109775 · NIMH · WASHINGTON UNIVERSITY · PI EGGEBRECHT, ADAM THOMAS · 2017 to 2018
$419k
NCI NIH HHS R01 CA132750NIMH NIH HHS K01 MH103594NIMH NIH HHS R21 MH109775NINDS NIH HHS R01 NS090874NINDS NIH HHS R01 NS099429
6 · The paper itself

Abstract

Parameter recovery in diffuse optical tomography is a computationally expensive algorithm, especially when used for large and complex volumes, as in the case of human brain functional imaging. The modeling of light propagation, also known as the forward problem, is the computational bottleneck of the recovery algorithm, whereby the lack of a real-time solution is impeding practical and clinical applications. The objective of this work is the acceleration of the forward model, within a diffusion approximation-based finite-element modeling framework, employing parallelization to expedite the calculation of light propagation in realistic adult head models. The proposed methodology is applicable for modeling both continuous wave and frequency-domain systems with the results demonstrating a 10-fold speed increase when GPU architectures are available, while maintaining high accuracy. It is shown that, for a very high-resolution finite-element model of the adult human head with ∼600,000 nodes, consisting of heterogeneous layers, light propagation can be calculated at ∼0.25  s/excitation source.

Indexed as

Tomography, OpticalAlgorithmsBrainComputer GraphicsHeadHumansdiffuse optical tomographyfinite-element methodGPUNIRFASTparallel computing

Identifiers

PMID29197176
PMCPMC5709934
OpenAlexW2773816631

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.