Evidence map›Paper›PMID 29197174›Full record

ArticleInfluenza and other respiratory viruses2018

Estimates of seasonal influenza-associated mortality in Bangladesh, 2010-2012.

Makhdum Ahmed, Mohammad Abdul Aleem, Katherine Roguski, Jaynal Abedin, Ariful Islam, Kazi Faisal Alam, Emily S Gurley, Mahmudur Rahman, Eduardo Azziz-Baumgartner, Nusrat Homaira and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05996549 (Acceptability, Cost-Effectiveness, and Capacity of a Facility-Based Seasonal Influenza Vaccination), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05996549 phase4unknown statusnot on this mapstarted 2022, after this paper: background citation

Acceptability, Cost-Effectiveness, and Capacity of a Facility-Based Seasonal Influenza Vaccination: A Study in Selected Hospitals of Bangladesh

TypeinterventionalSponsorInternational Centre for Diarrhoeal Disease Research, BangladeshRan2022 to 2024Enrolled2,567ConditionsInfluenza Vaccine, Cost-Effectiveness, VaccinationArmsQuadrivalent Influenza Vaccine
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Makhdum AhmedInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh, USA.ORCID 0000-0002-0772-8710
Mohammad Abdul AleemInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh, USA.
Katherine RoguskiCenters for Disease Control and Prevention, Atlanta, GA, USA.
Jaynal AbedinInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh, USA.
Ariful IslamInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh, USA.
Kazi Faisal AlamInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh, USA.
Emily S GurleyInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh, USA.
Mahmudur RahmanInstitute of Epidemiology, Disease Control and Research (IEDCR), Dhaka, Bangladesh.
Eduardo Azziz-BaumgartnerCenters for Disease Control and Prevention, Atlanta, GA, USA.
Nusrat HomairaInternational Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh, USA.
Katharine Sturm-RamirezCenters for Disease Control and Prevention, Atlanta, GA, USA.
A Danielle IulianoCenters for Disease Control and Prevention, Atlanta, GA, USA.

Funding

ADDRESSING EMERGING INFECTIOUS DISEASES IN BANGLADESHU01CI000628 · CI · INTERNATIONAL CTR/DIARRHOEAL DIS RES · PI LATRIELLE, SARA · 2009 to 2014
$21.1M
NCPDCID CDC HHS U01 CI000628
6 · The paper itself

Abstract

backgroundSeasonal influenza-associated mortality estimates help identify the burden of disease and assess the value of public health interventions such as annual influenza immunization. Vital registration is limited in Bangladesh making it difficult to estimate seasonal influenza mortality.

objectivesOur study aimed to estimate seasonal influenza-associated mortality rates for 2010-2012 in Bangladesh.

methodsWe conducted surveillance among hospitalized patients with severe acute respiratory illness (SARI) for persons aged ≥5 years and severe pneumonia for children <5 years in 11 sites across Bangladesh. We defined the catchment areas of these sites and conducted a community survey in 22 randomly selected unions (administrative units) within the catchment areas to identify respiratory deaths. We multiplied the proportion of influenza-positive patients at our surveillance sites by the age-specific number of respiratory deaths identified to estimate seasonal influenza-associated mortality.

resultsAmong 4221 surveillance case-patients, 553 (13%) were positive for influenza viruses. Concurrently, we identified 1191 persons who died within 2 weeks of developing an acute respiratory illness within the catchment areas of the surveillance hospitals. In 2010-2011, the estimated influenza-associated mortality rate was 6 (95% CI 4-9) per 100 000 for children <5 years and 41 (95% CI 35-47) per 100 000 for persons >60 years. During 2011-2012, the estimated influenza-associated mortality rate was 13 (95% CI 10-16) per 100 000 among children <5 years and 88 (95% CI 79-98) per 100 000 among persons aged >60 years.

conclusionsWe identified a substantial burden of influenza-associated deaths in Bangladesh suggesting that the introduction of prevention and control measures including seasonal vaccination should be considered by local public health decision-makers.

Indexed as

BangladeshCost of IllnessHumansInfluenza, HumanModels, BiologicalSeasonsSentinel SurveillanceBangladeshburdeninfluenzamortalityrespiratoryseasonal

Identifiers

PMID29197174
PMCPMC5818342

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.