Evidence map›Paper›PMID 29197091›Full record

Trial reportJournal of child psychology and psychiatry, and allied disciplines2018

Cost-effectiveness of cognitive therapy as an early intervention for post-traumatic stress disorder in children and adolescents: a trial based evaluation and model.

James Shearer, Nestor Papanikolaou, Richard Meiser-Stedman, Anna McKinnon, Tim Dalgleish, Patrick Smith, Clare Dixon, Sarah Byford

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of child psychology and psychiatry, and allied disciplines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

James ShearerKing's Health Economics, King's College London, London, UK.
Nestor PapanikolaouKing's Health Economics, King's College London, London, UK.
Richard Meiser-StedmanMedical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.ORCID 0000-0002-0262-623X
Anna McKinnonMedical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Tim DalgleishMedical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Patrick SmithInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Clare DixonMedical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Sarah ByfordKing's Health Economics, King's College London, London, UK.
King's College London · GBMRC Cognition and Brain Sciences Unit · GBUniversity of East Anglia · GB

Funding

Medical Research Council MC_EX_G0802821Medical Research Council MC_U105579215Medical Research Council MC_UU_00005/4
6 · The paper itself

Abstract

backgroundUntreated post-traumatic stress disorder (PTSD) in children and adolescents is associated with a considerable economic burden on the health system, families and society. Recent research has demonstrated the potential efficacy of cognitive therapy as an early intervention for PTSD in children and adolescents. Children who experienced a single traumatic event in the previous two to six months and were randomized to cognitive therapy for PTSD (CT-PTSD) were significantly more likely to be PTSD-free compared to those randomized to usual care represented by waitlist control. The current study evaluated the economic impact of improvements in the treatment of PTSD in children and adolescents.

methodsA cost-effectiveness analysis was conducted from the national health service/personal social services perspective with outcomes expressed as quality-adjusted life years (QALYs). Patient level costs and outcomes were collected during the 11 week clinical trial and extrapolated to a three year time horizon using economic modelling methods. Uncertainty was estimated using probabilistic sensitivity analysis and assumptions were tested using one way sensitivity analysis.

resultsThe incremental cost-effectiveness ratio at 3 years was £2,205 per QALY with a 60%-69% probability of CT-PTSD being cost-effective compared to usual care at the UK £20,000 to £30,000 per QALY decision threshold.

conclusionsThis study provides preliminary evidence for the cost-effectiveness of cognitive therapy in this treatment population. Larger pragmatic trials with longer follow-up are indicated.

Indexed as

Cost-Benefit AnalysisOutcome Assessment, Health CareQuality-Adjusted Life YearsAdolescentChildCognitive Behavioral TherapyEarly Medical InterventionFemaleFollow-Up StudiesHumansMaleModels, EconometricStress Disorders, Post-Traumaticcognitive therapyEconomic evaluationpost-traumatic stress disorder

Identifiers

PMID29197091
PMCPMC6597355
OpenAlexW2773837758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.