Evidence map›Paper›PMID 29197067›Full record

Trial reportInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2018

Cervical cancer screening through human papillomavirus testing in community health campaigns versus health facilities in rural western Kenya.

Megan J Huchko, Saduma Ibrahim, Cinthia Blat, Craig R Cohen, Jennifer S Smith, Robert A Hiatt, Elizabeth Bukusi

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02124252 (Evaluation of a Community-Driven Cervical Cancer Prevention Strategy in Western Kenya), which is not on this map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02124252 nacompletednot on this map

Evaluation of a Community-Driven Cervical Cancer Prevention Strategy in Western Kenya

TypeinterventionalSponsorDuke UniversityRan2016 to 2019Enrolled7,200ConditionsHuman Papilloma Virus Infection, Carcinoma in Situ of Uterine CervixArmsCommunity-based testing with standard linkage to care, Community-based HPV testing with enhanced linkage to care
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Megan J HuchkoDuke Global Health Institute, Duke University, Durham, NC, USA.
Saduma IbrahimCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Cinthia BlatDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA, USA.
Craig R CohenDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA, USA.
Jennifer S SmithDepartment of Epidemiology and Biostatistics, University of North Carolina, Chapel Hill, NC, USA.
Robert A HiattDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Elizabeth BukusiCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
University of California, San Francisco · USKenya Medical Research Institute · KEDuke University · USUniversity of North Carolina at Chapel Hill · US

Funding

Evaluating a community-driven cervical cancer prevention model in western KenyaR01CA188428 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUCHKO, MEGAN J. · 2014 to 2018
$2.5M
NCI NIH HHS R01 CA188428
6 · The paper itself

Abstract

objectiveTo determine the effectiveness of community health campaigns (CHCs) as a strategy for human papillomavirus (HPV)-based cervical cancer screening in rural western Kenya.

methodsBetween January and November 2016, a cluster-randomized trial was carried out in 12 communities in western Kenya to investigate high-risk HPV testing offered via self-collection to women aged 25-65 years in CHCs versus government health facilities. Outcome measures were the total number of women accessing cervical cancer screening and the proportion of HPV-positive women accessing treatment.

resultsIn total, 4944 women underwent HPV-based cervical cancer screening in CHCs (n=2898) or health facilities (n=2046). Screening uptake as a proportion of total eligible women in the population was greater in communities assigned to CHCs (60.0% vs 37.0%, P<0.001). Rates of treatment acquisition were low in both arms (CHCs 39.2%; health facilities 31.5%; P=0.408). DISCUSSION: Cervical cancer screening using HPV testing of self-collected samples reached a larger proportion of women when offered through periodic CHCs compared with health facilities. The community-based model is a promising strategy for cervical cancer prevention. Lessons learned from this trial can be used to identify ways of maximizing the impact of such strategies through greater community participation and improved linkage to treatment. ClinicalTrials.gov registration: NCT02124252.

Indexed as

Self-ExaminationAdultAgedCommunity ParticipationEarly Detection of CancerFemaleHealth FacilitiesHealth PromotionHumansKenyaMiddle AgedPapillomaviridaePapillomavirus InfectionsRural PopulationSpecimen HandlingUterine Cervical NeoplasmsCervical cancer screeningCommunity health campaignsHuman papillomavirus testingImplementation scienceKenyaSelf-collection

Identifiers

PMID29197067
PMCPMC7369666
OpenAlexW2774645261

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.