ReviewIn vitro cellular & developmental biology. Animal2017
Best practices for detecting and mitigating the risk of cell culture contaminants.
Review in In vitro cellular & developmental biology. Animal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Assessing the sensitisation hazard of microbial pesticides: potential value of New Approach Methodologies (NAMs) to overcome current challenges.Archives of toxicology · 2025Review
- A novel and simple workflow for investigating Mycoplasma spp. contamination in cell cultures.Folia microbiologica · 2025Article
- Random antimicrobial peptide mixtures as non-antibiotic antimicrobial agents for cultured meat industry.Food chemistry. Molecular sciences · 2025Article
- Bioreactor contamination monitoring using off-gassed volatile organic compounds (VOCs).Analytical and bioanalytical chemistry · 2025Article
- Review
- Antiobesity Drug Discovery Research:Current drug targets · 2024Review
- Navigating stem cell culture: insights, techniques, challenges, and prospects.Frontiers in cell and developmental biology · 2024Review
- Identification of cell culture contamination by an unusual species ofCytotechnology · 2023Article
- Review
- Highlights on Advancing Frontiers in Tissue Engineering.Tissue engineering. Part B, Reviews · 2022Review
- Isolation and feeder-free primary culture of four cell types from a single human skin sample.STAR protocols · 2022Article
- Report of a clinical and laboratory management of cell therapy for knee cartilage in the face of mycoplasma contamination.Einstein (Sao Paulo, Brazil) · 2022Article
- Safety Level of Microorganism-Bearing Products Applied in Soil-Plant Systems.Frontiers in plant science · 2022Review
- The Importance of Quality Control of LSDV Live Attenuated Vaccines for Its Safe Application in the Field.Vaccines · 2021Article
- A Chemically Defined Serum-Free Culture System for Spontaneous Human Mesenchymal Stem Cell Spheroid Formation.Stem cells international · 2020Article
- Prevalence of antibiotic resistance genes in cell culture liquid waste and the virulence assess for isolated resistant strains.Environmental science and pollution research international · 2019Article
- Best practices for authenticating cell lines.In vitro cellular & developmental biology. Animal · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A variety of biological and chemical contaminants can adversely impact cells in culture, ranging from outright destruction of the culture, mutation, phenotypic changes to relatively minor changes in morphology, or growth rate. There are various approaches to detecting and mitigating the risk of biological or microbial contaminants in cell cultures, and these are discussed in this article. Chemical contaminants typically arise from improper handling or sourcing of cell culture reagents, glassware, or other types of consumables. These and other sources of chemical contaminants of cell cultures are discussed. The occurrence of chemical contamination is mitigated through adherence to best practices in sourcing and handling of such materials and by avoiding the use of volatile solvents within incubators that are used for maintaining cell cultures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.