Evidence map›Paper›PMID 29196889›Full record

ArticleDermatology and therapy2018

Durable Resolution of Severe Psoriasis in a Patient Treated with Pentostatin for Hairy Cell Leukemia: A Case Report.

Tamim Alsuliman, Kaiss Lassoued, Maifa Belghoul, Karima Debbache, Bachra Choufi

Open access · goldAbstract read
In one paragraph

Article in Dermatology and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Purinergic Signaling and Inflammasome Activation in Psoriasis Pathogenesis.International journal of molecular sciences · 2021
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Tamim AlsulimanService d'Hématologie, Centre Hospitalier de Boulogne-Sur-Mer, Boulogne-Sur-Mer, France.
Kaiss LassouedService d'Hématologie, Centre Hospitalier de Boulogne-Sur-Mer, Boulogne-Sur-Mer, France.
Maifa BelghoulAugsburg College, Minneapolis, MN, USA.
Karima DebbacheService d'Hématologie, Centre Hospitalier de Boulogne-Sur-Mer, Boulogne-Sur-Mer, France.
Bachra ChoufiService d'Hématologie, Centre Hospitalier de Boulogne-Sur-Mer, Boulogne-Sur-Mer, France. b.choufi@gmail.com.ORCID http://orcid.org/0000-0001-7547-3783
Augsburg University · USCentre Hospitalier Universitaire Amiens-Picardie · FRCentre Hospitalier Universitaire de Lille · FRUniversité d'été de Boulogne-sur-Mer · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPentostatin (2'-deoxycoformycin) and cladribine (2-chlorodeoxyadenosine) are adenosine analogues widely used to treat lymphoid malignancies, mainly hairy cell leukemia (HCL). Oral or parenteral adenosine analogues have been also used as immunomodulatory agents in multiple sclerosis and in acute graft-versus-host disease. CASE REPORT: Here, we report the case of a 43-year-old patient with a history of extensive psoriasis who later developed HCL.

resultsThe patient had achieved complete remission of both psoriasis and HCL after receiving intravenous infusions of pentostatin. It is worth noting that cladribine has already been reported to treat plaque psoriasis lesions in two patients with HCL and in a third patient with gastric marginal zone B cell lymphoma [1].

conclusionWe believe that adenosine analogues constitute a promising therapeutic option for moderate to severe psoriasis, especially for severe and refractory psoriasis, as well as for patients with adjacent lymphoid malignancies.

Indexed as

Hairy cell leukemiaPentostatinPsoriasis

Identifiers

PMID29196889
PMCPMC5825321
OpenAlexW2771300430

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.