ArticleEuropean radiology2018
Ultrasound-ultrasound image overlay fusion improves real-time control of radiofrequency ablation margin in the treatment of hepatocellular carcinoma.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Efficacy of fusion imaging for immediate post-ablation assessment of malignant liver neoplasms: A systematic review.Cancer medicine · 2023Pooled it
- Quantitative Ablation Confirmation Methods in Percutaneous Thermal Ablation of Malignant Liver Tumors: Technical Insights, Clinical Evidence, and Future Outlook.Radiology. Imaging cancer · 2025Review
- Can Intra-Operative Ablation-Specific Features Based on Ultrasound Fusion Imaging be Used to Predict Early Recurrence of Hepatocellular Carcinoma After Microwave Ablation: A Proof-of-Concept Study.Journal of hepatocellular carcinoma · 2025Article
- Ablation manual for liver cancer.Journal of medical ultrasonics (2001) · 2025Review
- Precise liver tumor ablation: the clinical potential of US-US overlay fusion guidance.Ultrasonography (Seoul, Korea) · 2024Article
- Usefulness of Body Position Change during Local Ablation Therapies for the High-Risk Location Hepatocellular Carcinoma.Cancers · 2024Article
- Treatment options for solitary hepatocellular carcinoma ≤5 cm: surgery vs. ablation: a multicenter retrospective study.Journal of liver cancer · 2024Article
- Tips for Preparing and Practicing Thermal Ablation Therapy of Hepatocellular Carcinoma.Cancers · 2023Review
- Complications Risk Assessment and Imaging Findings of Thermal Ablation Treatment in Liver Cancers: What the Radiologist Should Expect.Journal of clinical medicine · 2022Review
- A novel mono-modality fusion imaging method based on three-dimensional contrast-enhanced ultrasound for the evaluation of ablation margins after microwave ablation of hepatocellular carcinoma.Journal of gastrointestinal oncology · 2021Article
- Image Guidance in Ablation for Hepatocellular Carcinoma: Contrast-Enhanced Ultrasound and Fusion Imaging.Frontiers in oncology · 2021Review
- Development of a method for measuring spleen stiffness by transient elastography using a new device and ultrasound-fusion method.PloS one · 2021Article
- Value of shear wave elastography with maximal elasticity in differentiating benign and malignant solid focal liver lesions.World journal of gastroenterology · 2020Article
- On the occasion of publication of the feature on differential diagnosis and treatment of hepatocellular carcinoma: the role of ultrasound.Journal of medical ultrasonics (2001) · 2020Article
- Ultrasound fusion imaging technologies for guidance in ablation therapy for liver cancer.Journal of medical ultrasonics (2001) · 2020Review
- Contrast-enhanced ultrasound to ultrasound fusion during microwave ablation: feasibility study in a perfused porcine liver model.Journal of ultrasound · 2019Article
- Effects of microbubble-enhanced ultrasound combined with prothrombin on microwave ablation in rabbit VX2 liver tumor.American journal of translational research · 2019Article
- Proposal for the Fusion of Ultrasound and Computed Tomography Images for Image Shift Correction in Craniomaxillofacial Soft Tissue Surgery.The Journal of craniofacial surgeryArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess the clinical feasibility of US-US image overlay fusion with evaluation of the ablative margin in radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC).
methodsFifty-three patients with 68 HCCs measuring 0.9-4.0 cm who underwent RFA guided by US-US overlay image fusion were included in this retrospective study. By an overlay of pre-/postoperative US, the tumor image could be projected onto the ablative hyperechoic zone. Therefore, the ablative margin three-dimensionally could be shown during the RFA procedure. US-US image overlay was compared to dynamic CT a few days after RFA for assessment of early treatment response. Accuracy of graded response was calculated, and the performance of US-US image overlay fusion was compared with that of CT using a Kappa agreement test.
resultsTechnically effective ablation was achieved in a single session, and 59 HCCs (86.8 %) succeeded in obtaining a 5-mm margin on CT. The response with US-US image overlay correctly predicted early CT evaluation with an accuracy of 92.6 % (63/68) (k = 0.67; 95 % CI: 0.39-0.95).
conclusionUS-US image overlay fusion can be proposed as a feasible guidance in RFA with a safety margin and predicts early response of treatment assessment with high accuracy. KEY POINTS: • US-US image overlay fusion visualizes the ablative margin during RFA procedure. • Visualizing the margin during the procedure can prompt immediate complementary treatment. • US image fusion correlates with the results of early evaluation CT.
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