ArticleEuropean journal of applied physiology2018
The availability of water associated with glycogen during dehydration: a reservoir or raindrop?
Article in European journal of applied physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 26 citations in OpenAlex.
- Trial
- Rapid water transfer from extracellular to intracellular spaces following oral ingestion.The journal of physiological sciences : JPS · 2026Article
- 24-Hour Ultra-Marathon Running: A Narrative Review of Performance Factors and Physiological Impacts.Sports medicine - open · 2026Review
- Short term body mass manipulation in powerlifting: a narrative review and best practice recommendations.Journal of the International Society of Sports Nutrition · 2025Review
- Compositional Aspects of Beverages Designed to Promote Hydration Before, During, and After Exercise: Concepts Revisited.Nutrients · 2023Review
- Ultra-Endurance Participation and Acute Kidney Injury: A Narrative Review.International journal of environmental research and public health · 2022Review
- Altered electrical properties in skeletal muscle of mice with glycogen storage disease type II.Scientific reports · 2022Article
- Changes in Intra-to-Extra-Cellular Water Ratio and Bioelectrical Parameters from Day-Before to Day-Of Competition in Bodybuilders: A Pilot Study.Sports (Basel, Switzerland) · 2022Article
- The impact of weather on the incidence of dark cutting in Australian feedlot cattle.International journal of biometeorology · 2022Article
- Peak week recommendations for bodybuilders: an evidence based approach.BMC sports science, medicine & rehabilitation · 2021Review
- Ad libitum drinking adequately supports hydration during 2 h of running in different ambient temperatures.European journal of applied physiology · 2018Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study evaluated whether glycogen-associated water is a protected entity not subject to normal osmotic homeostasis. An investigation into practical and theoretical aspects of the functionality of this water as a determinant of osmolality, dehydration, and glycogen concentration was undertaken.
methodsIn vitro experiments were conducted to determine the intrinsic osmolality of glycogen-potassium phosphate mixtures as would be found intra-cellularly at glycogen concentrations of 2% for muscle and 5 and 10% for liver. Protected water would not be available to ionic and osmotic considerations, whereas free water would obey normal osmotic constraints. In addition, the impact of 2 L of sweat loss in situations of muscle glycogen repletion and depletion was computed to establish whether water associated with glycogen is of practical benefit (e.g., to increase "available total body water").
resultsThe osmolality of glycogen-potassium phosphate mixtures is predictable at 2% glycogen concentration (predicted 267, measured 265.0 ± 4.7 mOsmol kg
conclusionGlycogen-associated water does not appear to be a separate reservoir and is not able to uniquely replete water loss during dehydration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.